[HTML][HTML] Pathogenesis of osteoarthritis: risk factors, regulatory pathways in chondrocytes, and experimental models
Y He, Z Li, PG Alexander, BD Ocasio-Nieves, L Yocum… - Biology, 2020 - mdpi.com
As the most common chronic degenerative joint disease, osteoarthritis (OA) is the leading
cause of pain and physical disability, affecting millions of people worldwide. Mainly …
cause of pain and physical disability, affecting millions of people worldwide. Mainly …
[HTML][HTML] An evidence-based systematic review of human knee post-traumatic osteoarthritis (PTOA): timeline of clinical presentation and disease markers, comparison …
CM Khella, R Asgarian, JM Horvath, B Rolauffs… - International Journal of …, 2021 - mdpi.com
Understanding the causality of the post-traumatic osteoarthritis (PTOA) disease process of
the knee joint is important for diagnosing early disease and developing new and effective …
the knee joint is important for diagnosing early disease and developing new and effective …
Post‐traumatic osteoarthritis of the ankle: a distinct clinical entity requiring new research approaches
ML Delco, JG Kennedy, LJ Bonassar… - Journal of Orthopaedic …, 2017 - Wiley Online Library
The diagnosis of ankle osteoarthritis (OA) is increasing as a result of advancements in non‐
invasive imaging modalities such as magnetic resonance imaging, improved arthroscopic …
invasive imaging modalities such as magnetic resonance imaging, improved arthroscopic …
[HTML][HTML] Osteoarthritis: a narrative review of molecular approaches to disease management
Osteoarthritis (OA) is a chronic, progressive degenerative whole joint disease that affects the
articular cartilage, subchondral bone, ligaments, capsule, and synovium. While it is still …
articular cartilage, subchondral bone, ligaments, capsule, and synovium. While it is still …
Targeting mitochondrial responses to intra-articular fracture to prevent posttraumatic osteoarthritis
MC Coleman, JE Goetz, MJ Brouillette, D Seol… - Science translational …, 2018 - science.org
We tested whether inhibiting mechanically responsive articular chondrocyte mitochondria
after severe traumatic injury and preventing oxidative damage represent a viable paradigm …
after severe traumatic injury and preventing oxidative damage represent a viable paradigm …
Changes in cytokines and aggrecan ARGS neoepitope in synovial fluid and serum and in C‐terminal crosslinking telopeptide of type II collagen and N‐terminal …
A Struglics, S Larsson, N Kumahashi… - Arthritis & …, 2015 - Wiley Online Library
Objective To prospectively monitor levels of proinflammatory cytokines and aggrecan ARGS
neoepitope in synovial fluid and serum as well as levels of C‐terminal crosslinking …
neoepitope in synovial fluid and serum as well as levels of C‐terminal crosslinking …
Autologous bone marrow concentrate: review and application of a novel intra-articular orthobiologic for cartilage disease
S Sampson, AB Bemden, D Aufiero - The Physician and …, 2013 - Taylor & Francis
Abstract Younger adults, aged< 65 years, increasingly present to their physicians with
advanced cartilage disease or post-traumatic osteoarthritis. A number of treatments exist for …
advanced cartilage disease or post-traumatic osteoarthritis. A number of treatments exist for …
[HTML][HTML] Pathomechanisms of posttraumatic osteoarthritis: chondrocyte behavior and fate in a precarious environment
J Riegger, RE Brenner - International journal of molecular sciences, 2020 - mdpi.com
Traumatic injuries of the knee joint result in a wide variety of pathomechanisms, which
contribute to the development of so-called posttraumatic osteoarthritis (PTOA). These …
contribute to the development of so-called posttraumatic osteoarthritis (PTOA). These …
[HTML][HTML] Protoplast Isolation and Shoot Regeneration from Protoplast-Derived Callus of Petunia hybrida Cv. Mirage Rose
Despite the increasing use of protoplasts in plant biotechnology research, shoot
regeneration from protoplasts remains challenging. In this study, we investigated the factors …
regeneration from protoplasts remains challenging. In this study, we investigated the factors …
Mitochondrial dysfunction is an acute response of articular chondrocytes to mechanical injury
Mitochondrial (MT) dysfunction is known to occur in chondrocytes isolated from end‐stage
osteoarthritis (OA) patients, but the role of MT dysfunction in the initiation and early …
osteoarthritis (OA) patients, but the role of MT dysfunction in the initiation and early …