The effects of vitamin D on immune system and inflammatory diseases

T Ao, J Kikuta, M Ishii - Biomolecules, 2021 - mdpi.com
Immune cells, including dendritic cells, macrophages, and T and B cells, express the vitamin
D receptor and 1α-hydroxylase. In vitro studies have shown that 1, 25-dihydroxyvitamin D …

Systemic lupus erythematosus: diagnosis and clinical management

A Fava, M Petri - Journal of autoimmunity, 2019 - Elsevier
Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which
may affect every organ and tissue. Genetic predisposition, environmental triggers, and the …

[HTML][HTML] COVID-19 mortality risk correlates inversely with vitamin D3 status, and a mortality rate close to zero could theoretically be achieved at 50 ng/mL 25 (OH) D3 …

L Borsche, B Glauner, J von Mendel - Nutrients, 2021 - mdpi.com
Background: Open Access Editor's Choice Systematic Review COVID-19 Mortality Risk
Correlates Inversely with Vitamin D3 Status, and a Mortality Rate Close to Zero Could …

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

X Jiang, PF O'Reilly, H Aschard, YH Hsu… - Nature …, 2018 - nature.com
Vitamin D is a steroid hormone precursor that is associated with a range of human traits and
diseases. Previous GWAS of serum 25-hydroxyvitamin D concentrations have identified four …

Obesity in autoimmune diseases: not a passive bystander

M Versini, PY Jeandel, E Rosenthal, Y Shoenfeld - Autoimmunity reviews, 2014 - Elsevier
In the last decades, autoimmune diseases have experienced a dramatic increase in Western
countries. The involvement of environmental factors is strongly suspected to explain this rise …

Immunomodulatory effects of vitamin D in pregnancy and beyond

F Cyprian, E Lefkou, K Varoudi, G Girardi - Frontiers in immunology, 2019 - frontiersin.org
In addition to its role in calcium homeostasis and bone formation, a modulatory role of the
active form of vitamin D on cells of the immune system, particularly T lymphocytes, has been …

[HTML][HTML] PTH and vitamin D

SJ Khundmiri, RD Murray, E Lederer - Comprehensive Physiology, 2016 - ncbi.nlm.nih.gov
PTH and Vitamin D are two major regulators of mineral metabolism. They play critical roles
in the maintenance of calcium and phosphate homeostasis as well as the development and …

Fat-soluble vitamins: updated review of their role and orchestration in human nutrition throughout life cycle with sex differences

RA Youness, A Dawoud, O ElTahtawy, MA Farag - Nutrition & Metabolism, 2022 - Springer
Age and Gender are vital determinants for the micronutrient demands of normal indviduals.
Among these micronutrients are vitamins that are required in small amounts for optimum …

Vitamin D deficiency, osteoporosis and effect on autoimmune diseases and hematopoiesis: a review

M De Martinis, A Allegra, MM Sirufo, A Tonacci… - International journal of …, 2021 - mdpi.com
Vitamin D (VD) is essential for bone homeostasis, but it is also involved in pleiotropic effects
on various organs and tissues. In adults, VD deficiency can cause or exacerbate …

[HTML][HTML] Vitamin D-cathelicidin axis: at the crossroads between protective immunity and pathological inflammation during infection

C Chung, P Silwal, I Kim, RL Modlin, EK Jo - Immune network, 2020 - ncbi.nlm.nih.gov
Vitamin D signaling plays an essential role in innate defense against intracellular
microorganisms via the generation of the antimicrobial protein cathelicidin. In addition to …