Iron is an essential micronutrient for a myriad of physiological processes in the body beyond
erythropoiesis. Iron deficiency (ID) is a common comorbidity in patients with heart failure …

Hepatocellular carcinoma is the most prevalent form of primary liver cancer with a
multifactorial aetiology comprising genetic, environmental, and behavioural factors. Evading …

Ischemic heart disease is a leading cause of death worldwide. Primarily, ischemia causes
decreased oxygen supply, resulting in damage of the cardiac tissue. Naturally …

Iron is an essential mineral participating in different functions of the organism under
physiological conditions. Numerous biological processes, such as oxygen and lipid …

Heart disease is the leading cause of death worldwide. Cardiomyopathy is a disease
characterized by the heart muscle damage, resulting heart in a structurally and functionally …

Ferroptosis is an iron-and lipid peroxidation (LPO)-mediated programmed cell death type.
Recently, mounting evidence has indicated the involvement of ferroptosis in …

Palmitic acid (PA)-induced myocardial injury is considered a critical contributor to the
development of obesity and type 2 diabetes mellitus (T2DM)-related cardiomyopathy …

Acute myocardial infarction remains the leading cause of death in humans. Timely
restoration of blood perfusion to ischemic myocardium remains the most effective strategy in …

Hereditary iron overload includes several disorders characterized by iron accumulation in
tissues, organs, or even single cells or subcellular compartments. They are determined by …

To date, 3 clinical trials have shown symptomatic benefit from the use of intravenous (IV) iron
in patients with heart failure (HF) with low serum iron. This has led to recommendations in …