Mitochondrial fusion: the machineries in and out

S Gao, J Hu - Trends in cell biology, 2021 - cell.com
Mitochondria are highly dynamic organelles that constantly undergo fission and fusion.
Disruption of mitochondrial dynamics undermines their function and causes several human …

Dietary supplements and natural products: an update on their clinical effectiveness and molecular mechanisms of action during accelerated biological aging

Y Chen, S Hamidu, X Yang, Y Yan, Q Wang, L Li… - Frontiers in …, 2022 - frontiersin.org
Accelerated biological aging, which involves the gradual decline of organ or tissue functions
and the distortion of physiological processes, underlies several human diseases. Away from …

[HTML][HTML] Structural and functional roles of non-bilayer lipid phases of chloroplast thylakoid membranes and mitochondrial inner membranes

G Garab, LS Yaguzhinsky, O Dlouhý… - Progress in Lipid …, 2022 - Elsevier
The 'standard'fluid-mosaic membrane model can provide a framework for the operation of
the photosynthetic and respiratory electron transport systems, the generation of the proton …

Cardiolipin, non-bilayer structures and mitochondrial bioenergetics: Relevance to cardiovascular disease

ES Gasanoff, LS Yaguzhinsky, G Garab - Cells, 2021 - mdpi.com
The present review is an attempt to conceptualize a contemporary understanding about the
roles that cardiolipin, a mitochondrial specific conical phospholipid, and non-bilayer …

[HTML][HTML] Protein quality control at the mitochondrial surface

F den Brave, A Gupta, T Becker - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Mitochondria contain two membranes, the outer and inner membrane. The outer membrane
fulfills crucial functions for the communication of mitochondria with the cellular environment …

Mitochondrial surveillance by Cdc48/p97: MAD vs. membrane fusion

M Escobar-Henriques, V Anton - International Journal of Molecular …, 2020 - mdpi.com
Cdc48/p97 is a ring-shaped, ATP-driven hexameric motor, essential for cellular viability. It
specifically unfolds and extracts ubiquitylated proteins from membranes or protein …

[PDF][PDF] E4 ubiquitin ligase promotes mitofusin turnover and mitochondrial stress response

V Anton, I Buntenbroich, T Simões, M Joaquim… - Molecular Cell, 2023 - cell.com
Ubiquitin-dependent control of mitochondrial dynamics is important for protein quality and
neuronal integrity. Mitofusins, mitochondrial fusion factors, can integrate cellular stress …

[PDF][PDF] Docking and stability defects in mitofusin highlight the proteasome as a potential therapeutic target

I Buntenbroich, V Anton, D Perez-Hernandez, T Simões… - Iscience, 2023 - cell.com
Defects in mitochondrial fusion are at the base of many diseases. Mitofusins power
membrane-remodeling events via self-interaction and GTP hydrolysis. However, how exactly …

[PDF][PDF] Non-bilayer lipid phases modulate the structure and functions of mitochondrial membranes: pharmacological relevance

Y Han, Y Tao, ES Gasanoff - Am J Biomed Sci Res, 2023 - researchgate.net
This review is an attempt to elucidate the contemporary understanding of the role of non-
bilayer lipid phases in mitochondrial bioenergetics. It is based on the critical review of …

Structural and Functional Roles of Non-bilayer Lipid Phase in Mitochondria

Y Tao, ES Gasanoff - 2023 - europepmc.org
In this review article we critically discuss the experimental data that support existence of non-
bilayer lipid phase in intact mitochondria. We also review contemporary concepts on the role …