Gastric cancer: translating novels concepts into clinical practice

M Salati, G Orsi, E Smyth, G Beretta, F De Vita… - Cancer treatment …, 2019 - Elsevier
The overall 5-year survival of gastric cancer (GC) has change only little in the last decades
and it remains the fifth leading cause of cancer-related death worldwide. However, in the …

Prognostic and predictive value of microsatellite instability, inflammatory reaction and PD‐L1 in gastric cancer patients treated with either adjuvant 5‐FU/LV or …

M Di Bartolomeo, F Morano, A Raimondi… - The …, 2020 - academic.oup.com
Background Patients with high microsatellite instability (MSI) gastric cancer (GC) show
improved survival and no benefit or harm from adjuvant and/or perioperative chemotherapy …

Multimodal treatment in locally advanced gastric cancer

OT Goetze, SE Al-Batran, M Chevallay, SP Mönig - Updates in surgery, 2018 - Springer
According to the data of the GLOBOCAN-network of the World Health Organization, there
were 952,000 (6.8% of the total) new cases of gastric cancer in 2012, making it the fifth most …

EBV and MSI status in gastric cancer: does it matter?

CN do Nascimento, L Mascarenhas-Lemos, JR Silva… - Cancers, 2022 - mdpi.com
Simple Summary Gastric cancer is characterized by high morphologic and molecular
heterogeneity. Microsatellite instability (MSI-high) and Epstein–Barr-virus-positive (EBV+) …

Multimodality treatment for localized gastric cancer: state of the art and new insights

A Petrillo, EC Smyth - Current Opinion in Oncology, 2020 - journals.lww.com
Multimodality treatment represents the standard of care for resectable gastric cancer.
Perioperative chemotherapy with FLOT is the standard treatment in western countries; in …

The efficacy and safety of (neo) adjuvant therapy for gastric cancer: a network meta-analysis

T van den Ende, E Ter Veer, M Machiels, RMA Mali… - Cancers, 2019 - mdpi.com
Background: Alternatives in treatment-strategies exist for resectable gastric cancer. Our aims
were:(1) to assess the benefit of perioperative, neoadjuvant and adjuvant treatment …

Perioperative immune checkpoint inhibitor therapy for gastric and gastroesophageal junction cancers: a review of current approaches and future perspectives

D Takahari, I Nakayama - International Journal of Clinical Oncology, 2023 - Springer
Metastatic gastric and gastroesophageal junction cancers have been treated with
chemotherapy, but the landscape of cancer treatment is rapidly shifting towards immune …

Neoadjuvant chemotherapy for locally advanced gastric cancer in Japan: Consensus meeting at the 77th general meeting of the Japanese Society of …

M Tokunaga, Y Kurokawa, T Fukagawa… - Annals of …, 2023 - Wiley Online Library
Abstract Treatment strategy for locally advanced gastric cancer differs worldwide.
Neoadjuvant chemotherapy (NAC) is considered one of the promising treatment options for …

[HTML][HTML] Preoperative versus postoperative docetaxel–cisplatin–fluorouracil (TCF) chemotherapy in locally advanced resectable gastric carcinoma: 10-year follow-up …

N Fazio, R Biffi, R Maibach, S Hayoz, S Thierstein… - Annals of …, 2016 - Elsevier
Background Fluorouracil-based adjuvant chemotherapy in gastric cancer has been reported
to be effective by several meta-analyses. Perioperative chemotherapy in locally advanced …

Biomarker evaluation in radically resectable locally advanced gastric cancer treated with neoadjuvant chemotherapy: an evidence reappraisal

L Gervaso, S Pellicori, CA Cella… - … in medical oncology, 2021 - journals.sagepub.com
Neoadjuvant chemotherapy (NAC) significantly improved the prognosis of patients with
locally advanced resectable gastric cancer but, despite important progresses, relapse …