Current controversies in low-risk differentiated thyroid cancer: reducing overtreatment in an era of overdiagnosis

TM Ullmann, M Papaleontiou… - The Journal of Clinical …, 2023 - academic.oup.com
Context Low-risk differentiated thyroid cancer (DTC) is overdiagnosed, but true incidence
has increased as well. Owing to its excellent prognosis with low morbidity and mortality …

Progress and challenges in thyroid cancer management

MR Haymart - Endocrine Practice, 2021 - Elsevier
The state of thyroid cancer in 2021 is reviewed including the prevalence of thyroid cancer,
vulnerable patient groups such as women and young adults, and known and hypothesized …

Effect of TSH suppression therapy on bone mineral density in differentiated thyroid cancer: a systematic review and meta-analysis

EJ Ku, WS Yoo, EK Lee, HY Ahn… - The Journal of …, 2021 - academic.oup.com
Context Because subclinical hyperthyroidism increases the risk of osteoporosis and
fractures, concerns are growing about the long-term skeletal safety of TSH suppression …

[HTML][HTML] The relationship between thyrotropin serum concentrations and thyroid carcinoma

X Zhang, L Tian, D Teng, W Teng - Cancers, 2023 - mdpi.com
Simple Summary Thyroid-stimulating hormone (TSH) plays a role in the regulation of thyroid
hormones and is an important indicator for assessing thyroid function. Thyroid cancer (TC) is …

Circ_100395 impedes malignancy and glycolysis in papillary thyroid cancer: Involvement of PI3K/AKT/mTOR signaling pathway

LD Chen, DQ Zhuo, HY Yuan - Immunology Letters, 2022 - Elsevier
Circular RNAs (circRNAs) play critical roles in cancer procession, including papillary thyroid
cancer (PTC). Despite of published reports regarding the abnormal downregulation of …

Differentiated thyroid cancer: a focus on post-operative thyroid hormone replacement and thyrotropin suppression therapy

BJ Gigliotti, S Jasim - Endocrine, 2024 - Springer
Purpose This review focuses on post-operative thyroid hormone replacement and
thyrotropin suppression therapy in patients with differentiated thyroid cancer. Methods A …

[HTML][HTML] Thyroid cancer

K Lee, C Anastasopoulou, C Chandran… - StatPearls …, 2023 - ncbi.nlm.nih.gov
Objectives: Outline the epidemiology and risk factors of thyroid cancer. Describe the clinical
presentation and detailed histopathology of the different types of thyroid cancer. Explain the …

HIF‐1α regulates the cell viability in radioiodine‐resistant papillary thyroid carcinoma cells induced by hypoxia through PKM2/NF‐κB signaling pathway

D Wang, X Liu, M Li, J Ning - Molecular Carcinogenesis, 2024 - Wiley Online Library
The curative treatment options for papillary thyroid cancer (PTC) encompass surgical
intervention, radioactive iodine administration, and chemotherapy. However, the challenges …

[HTML][HTML] Is maintaining thyroid-stimulating hormone effective in patients undergoing thyroid lobectomy for low-risk differentiated thyroid cancer? A systematic review …

HR Won, E Jeon, JW Chang, YE Kang, K Song… - Cancers, 2022 - mdpi.com
Simple Summary In order to reduce the recurrence rate after surgical treatment of
differentiated thyroid cancer (DTC), suppression of thyroid-stimulating hormone (TSH) or …

Towards de-implementation of low-value thyroid care in older adults

JM Perkins, M Papaleontiou - Current Opinion in Endocrinology …, 2022 - journals.lww.com
Towards De-Implementation of low-value thyroid care in older... : Current Opinion in
Endocrinology, Diabetes and Obesity Towards De-Implementation of low-value thyroid care in …