Could endothelin-1 be a promising neurohormonal biomarker in acute heart failure?

BA Dmour, AD Costache, A Dmour, B Huzum, ȘT Duca… - Diagnostics, 2023 - mdpi.com
Acute heart failure (AHF) is a life-threatening condition with high morbidity and mortality.
Even though this pathology has been extensively researched, there are still challenges in …

Spotlight on HOX cluster‑embedded antisense lncRNAs in cardiovascular diseases

Y Zhou, Q Wu - International Journal of Molecular …, 2023 - spandidos-publications.com
Atherosclerosis is a complex and chronic inflammatory disease driven by multiple
pathophysiological processes that are responsible for diverse cardiovascular events …

Monocrotaline-induced pulmonary arterial hypertension and bosentan treatment in rats: focus on plasma and erythrocyte parameters

T Jasenovec, D Radosinska, M Kollarova, N Vrbjar… - Pharmaceuticals, 2022 - mdpi.com
The objective of our study was to contribute to the characterization of monocrotaline-induced
pulmonary arterial hypertension (PAH) in a rat model, with emphasis on the renin …

Continuous heart monitoring to evaluate treatment effects in pulmonary hypertension

MØ Andersen, SZ Diederichsen, JH Svendsen… - Open …, 2024 - openheart.bmj.com
Background The treatment of pulmonary hypertension (PH) has improved rapidly in recent
decades. There is increasing evidence to support the role of early intervention and treatment …

Long-term efficacies of selective vasodilators in pulmonary arterial hypertension: A comprehensive comparison using a spontaneous reporting database

K Suzuki, T Yagi, J Kawakami - Naunyn-Schmiedeberg's Archives of …, 2024 - Springer
There is no clinical evidence of differences in drugs associated with long-term survival in
patients with pulmonary arterial hypertension (PAH) due to the small population and lack of …

Drug‐Drug Interaction between Oral Zamicastat and Continuous Epoprostenol Infusion at Steady‐State Conditions in Healthy Subjects

M Fonseca, A Guimarães, H Gama… - The Journal of …, 2024 - Wiley Online Library
This study intended to evaluate the interactions between zamicastat and epoprostenol in
healthy human subjects. This was a single‐center, open‐label, two‐period study. In period …

[HTML][HTML] 槲皮素可改善大鼠肺动脉高压: 基于调控HMGB1/RAGE/NF-κB 通路

张宁宁, 邱奇, 陈永锋, 孙正宇, 卢国庆… - Journal of Southern …, 2023 - ncbi.nlm.nih.gov
槲皮素可改善大鼠肺动脉高压: 基于调控HMGB1/RAGE/NF-κB通路- PMC Back to Top Skip to
main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content …

Quercetin improves pulmonary arterial hypertension in rats by regulating the HMGB1/RAGE/NF-κB pathway

N Zhang, Q Qiu, Y Chen, Z Sun, G Lu… - … Fang yi ke da xue xue …, 2023 - europepmc.org
Methods Rat models of hypoxic pulmonary hypertension were established by exposure to
hypoxia for 8-10 h each day (6 days a week for 4 weeks), and before each hypoxic …

Automatic Edge Detection in Echocardiographic Doppler Images Using an Improved Canny Algorithm

Y Liu, B Peng, Z Liang, X Zhu… - 2023 12th …, 2023 - ieeexplore.ieee.org
This paper introduces an optimized edge detection algorithm for the detection of tricuspid
regurgitant jet velocity (TRV) trace edges in echocardiographic Doppler images of patients …

KLF6 in Pulmonary Hypertension: The Dual Role of Friend and Foe

R Alharbi, N Fernandes, H Maude, A Fellows… - bioRxiv, 2024 - biorxiv.org
Background: Pulmonary arterial hypertension (PAH) is a severe lung condition with an
unmet clinical need. Endothelial damage is followed by excessive repair and narrowing of …