Background Despite growing interest, there is no guidance or consensus on how to conduct
clinical trials and observational studies in populations at risk of rheumatoid arthritis (RA) …

The tumor microenvironment is overwhelmingly dictated by macrophages, intimately
affiliated with tumors, exercising pivotal roles in multiple processes, including angiogenesis …

Rheumatoid arthritis (RA) is an autoimmune disease that involves T and B cells and their
reciprocal immune interactions with proinflammatory cytokines. T cells, an essential part of …

Recruitment of immune cells from the vasculature relies on the presentation of
glycosaminoglycan-bound chemokines on the luminal side of vascular endothelial cells …

Objectives To validate the presence and demonstrate the clinical value of the type I
interferon (IFN)-signature during arthritis development. Method In 115 seropositive arthralgia …

RA is a complex multifactorial chronic disease that transitions through several stages.
Multiple studies now support that there is a prolonged phase in early RA development …

The article discusses the study on rheutomatoid arthritis (RA) with regard to whether
localized autoimmunity is a crucial trigger in preclinical disease. The novel immunologic and …

Objective. IL-9 has been shown to be upregulated before the clinical onset of articular
disease in RA. The exact role of IL-9 and Th9 cells in RA, however, has not yet been …

Correlation analysis of red blood cell distribution width (RDW) and C-reactive protein (CRP),
erythrocyte sedimentation rate (ESR), tumor necrosis factor α (TNF-α), interleukin (IL)-6, and …

We have recently developed betalain-rich beetroot (Beta vulgaris) dye (betalain) to be used
in food products. Betalain (30–300 mg/kg) intraperitoneal (ip) treatment diminished …