[PDF][PDF] The preclinical phase of rheumatoid arthritis: what is acknowledged and what needs to be assessed

HW Van Steenbergen, TW Huizinga… - Arthritis …, 2013 - scholarlypublications …
Rheumatoid arthritis (RA) affects 1% of the population worldwide and is characterised by
persistent inflammation and joint damage. It has repeatedly been observed that early …

Perceived stress and inflammatory arthritis: a prospective investigation in the studies of the etiologies of rheumatoid arthritis cohort

KJ Polinski, EA Bemis, M Feser, J Seifert… - Arthritis care & …, 2020 - Wiley Online Library
Objective The aim of this study was to determine the association of perceived stress with
incident inflammatory arthritis (IA) defined as having at least 1 joint consistent with …

Preclinical rheumatoid arthritis (autoantibodies): an updated review

KD Deane - Current rheumatology reports, 2014 - Springer
Multiple studies demonstrate that there is a period of development of rheumatoid arthritis
(RA) during which there are elevations of disease-related biomarkers, including …

Survivin a pivotal antiapoptotic protein in rheumatoid arthritis

P Zafari, A Rafiei, SA Esmaeili… - Journal of cellular …, 2019 - Wiley Online Library
Rheumatoid arthritis (RA) is an autoimmune disease, pathologically characterized by
lymphocyte infiltration of the synovial membrane that leads to chronic inflammation and …

Cohort profile: SCREEN-RA: design, methods and perspectives of a Swiss cohort study of first-degree relatives of patients with rheumatoid arthritis

BTP Gilbert, C Lamacchia, D Mongin, K Lauper… - BMJ open, 2021 - bmjopen.bmj.com
Purpose Rheumatoid arthritis (RA) is an insidious autoimmune disease, with an
immunological onset years before diagnosis. Early interventions in preclinical stages could …

Increased serum interleukin‐9 levels in rheumatoid arthritis and systemic lupus erythematosus: pathogenic role or just an epiphenomenon?

AT Dantas, CDL Marques, LF da Rocha Junior… - Disease …, 2015 - Wiley Online Library
The purpose of this paper was to evaluate the levels of IL‐9 in patients with SLE and RA
compared with controls and the association of IL‐9 levels with clinical and laboratory …

Antibody arrays in biomarker discovery

JJ Wilson, R Burgess, YQ Mao, S Luo, H Tang… - Advances in clinical …, 2015 - Elsevier
All of life is regulated by complex and organized chemical reactions that help dictate when to
grow, to move, to reproduce, and to die. When these processes go awry, or are interrupted …

Alpha-glucosidase inhibitors alter gut microbiota and ameliorate collagen-induced arthritis

L Zhang, P Song, X Zhang, C Metea… - Frontiers in …, 2020 - frontiersin.org
Acarose is an anti-diabetic drug and exhibits anti-arthritic effects. We hypothesized that
acarbose influences the gut microbiota to affect the course of arthritis and tested this …

Rheumatoid arthritis:'melting pot'of T helper subsets

SP Vyas, AK Hansda, R Goswami - International reviews of …, 2019 - Taylor & Francis
Rheumatoid arthritis (RA) is an autoimmune disorder that affects joints associated with
inflammation leading to poor quality of life. The phenotype of RA is distinct from osteoarthritis …

CXCR3 antagonist AMG487 inhibits glucocorticoid-induced tumor necrosis factor-receptor-related protein and inflammatory mediators in CD45 expressing cells in …

SA Bakheet, BS Alrwashied, MA Ansari… - International …, 2020 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease classified by uncontrolled joint
inflammation leading to the destruction of both cartilage and joints. Despite progress made …