Objective To investigate the risk of progression to rheumatoid arthritis (RA) in patients who
were cyclic citrullinated peptide (CCP) antibody positive without RA at initial presentation …

Various subtypes of effector T cells have been described up to date, and each one has its
specific immunological function and a defined cytokine secretion profile. Th9 lymphocytes …

Methods We searched the PubMed database on January 29, 2014, for the terms risk,
prediction, and development in relation to RA. After excluding articles not directly related to …

Background Animal experiments have shown the anticancer activity of Toxoplasma gondii
(T. gondii), but its effect on the prognosis of cancer patients is unclear. Thus, the present …

Rheumatoid arthritis (RA) is a chronic debilitating autoimmune disease, that causes joint
damage, deformities, and decreased functionality. In addition, RA can also impact organs …

Background: Anti-inflammatory drugs and DMARDs, especially methotrexate, have
dramatically improved the outlook of RA patient. However, in some patients the treatment …

Objectives The aim of this study was to investigate the role of IL-1β (− 511C> T), TNFα (-308
G> A), IL-10 (-1082 G> A) and IL-1RN VNTR polymorphisms in the susceptibility to …

Inflammatory bowel disease is a chronic and progressive disorder of the gastrointestinal
tract. A relevant proportion of patients develop complicated lesions, defined as strictures …

Th9 cells, a subset of T-helper cells producing interleukin-9 (IL-9), play a vital role in the
adaptive immune response and have diverse effects in different diseases. Regulated by …

Behçet disease (BD) is a multisystemic disease some of whose manifestations are
characterized by pulmonary involvements. The purpose of the study was to evaluate the …