[HTML][HTML] Toward building mass spectrometry-based metabolomics and lipidomics atlases for biological and clinical research

S Rakusanova, O Fiehn, T Cajka - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Current metabolomics and lipidomics studies are limited in the number of examined
matrices, the breadth and scope of methods, reporting the number of metabolites, and data …

From omics to multi-omics approaches for in-depth analysis of the molecular mechanisms of prostate cancer

E Nevedomskaya, B Haendler - International Journal of Molecular …, 2022 - mdpi.com
Cancer arises following alterations at different cellular levels, including genetic and
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …

Evaluation of data-dependent MS/MS acquisition parameters for non-targeted metabolomics and molecular networking of environmental samples: Focus on the Q …

P Stincone, AK Pakkir Shah, R Schmid… - Analytical …, 2023 - ACS Publications
Non-targeted liquid chromatography–tandem mass spectrometry (LC–MS/MS) is a widely
used tool for metabolomics analysis, enabling the detection and annotation of small …

Optimization of mobile phase modifiers for fast LC-MS-based untargeted metabolomics and lipidomics

T Cajka, J Hricko, L Rudl Kulhava, M Paucova… - International Journal of …, 2023 - mdpi.com
Liquid chromatography-mass spectrometry (LC-MS) is the method of choice for the
untargeted profiling of biological samples. A multiplatform LC-MS-based approach is …

Quantification of snake venom proteomes by mass spectrometry‐considerations and perspectives

JJ Calvete, B Lomonte, AJ Saviola… - Mass Spectrometry …, 2023 - Wiley Online Library
The advent of soft ionization mass spectrometry‐based proteomics in the 1990s led to the
development of a new dimension in biology that conceptually allows for the integral analysis …

A glimmer of hope–ash genotypes with increased resistance to ash dieback pathogen show cross‐resistance to emerald ash borer

MM Gossner, A Perret‐Gentil, E Britt, V Queloz… - New …, 2023 - Wiley Online Library
Plants rely on cross‐resistance traits to defend against multiple, phylogenetically distinct
enemies. These traits are often the result of long co‐evolutionary histories. Biological …

An off-line three-dimensional liquid chromatography/Q-Orbitrap mass spectrometry approach enabling the discovery of 1561 potentially unknown ginsenosides from …

L Jia, H Wang, X Xu, H Wang, X Li, Y Hu… - … of Chromatography A, 2022 - Elsevier
To comprehensively elucidate the herbal metabolites is crucial in natural products research
to discover new lead compounds. Ginsenosides are an important class of bioactive …

Comparison between 5 extractions methods in either plasma or serum to determine the optimal extraction and matrix combination for human metabolomics

M Lepoittevin, Q Blancart-Remaury, T Kerforne… - Cellular & Molecular …, 2023 - Springer
Background Although metabolomics continues to expand in many domains of research,
methodological issues such as sample type, extraction and analytical protocols have not …

Dynamic interactomics by cross-linking mass spectrometry: Mapping the daily cell life in postgenomic Era

L Santorelli, M Caterino, M Costanzo - OMICS: A Journal of …, 2022 - liebertpub.com
The majority of processes that occur in daily cell life are modulated by hundreds to
thousands of dynamic protein–protein interactions (PPI). The resulting protein complexes …

Proteomic approaches to study ubiquitinomics

I Sahu, H Zhu, SJ Buhrlage, JA Marto - Biochimica et Biophysica Acta (BBA) …, 2023 - Elsevier
As originally described some 40 years ago, protein ubiquitination was thought to serve
primarily as a static mark for protein degradation. In the ensuing years, it has become clear …