In silico evaluation of pharmacokinetics and acute toxicity of withanolides in Ashawagandha
Y Liu - Phytochemistry Letters, 2022 - Elsevier
Ashwagandha is a medicinal plant used in traditional Asian medicines as an adaptogen to
promote both physical and mental health. Withanolides are the major bioactive …
promote both physical and mental health. Withanolides are the major bioactive …
[HTML][HTML] Neuroprotective effect of Withania somnifera leaves extract nanoemulsion against penconazole-induced neurotoxicity in albino rats via modulating TGF-β1 …
M Abomosallam, BM Hendam, AA Abdallah… - …, 2024 - Springer
Penconazole (PEN) is a systemic triazole fungicide used to control various fungal diseases
on grapes, stone fruits, cucurbits, and strawberries. Still, it leaves residues on treated crops …
on grapes, stone fruits, cucurbits, and strawberries. Still, it leaves residues on treated crops …
In Silico Prediction of Potential Inhibitors for Targeting RNA CAG Repeats via Molecular Docking and Dynamics Simulation: A Drug Discovery Approach
S Singh, S Singh, D Joshi, C Mohanty… - Journal of Cellular …, 2024 - Wiley Online Library
Spinocerebellar ataxia (SCA) is a rare neurological illness inherited dominantly that causes
severe impairment and premature mortality. While each rare disease may affect individuals …
severe impairment and premature mortality. While each rare disease may affect individuals …
Mitochondria Modulating Therapeutic Approaches in the Management of Huntington's Disease
This review highlights the therapeutic potential of mitochondrial drug targeting and
limitations of currently available mitochondria-targeted drugs (synthetic and natural …
limitations of currently available mitochondria-targeted drugs (synthetic and natural …
[HTML][HTML] Navigating neurological disorders: harnessing the power of natural compounds for innovative therapeutic breakthroughs
Novel treatments are needed as neurological issues become more frequent worldwide.
According to the report, plants, oceans, microorganisms, and animals contain interesting …
According to the report, plants, oceans, microorganisms, and animals contain interesting …
Role of Withania somnifera (Ashwagandha) in the treatment of neurological disorders
S Sharma - Current Nutrition & Food Science, 2023 - ingentaconnect.com
Different formulations of ashwagandha have been utilized for the treatment of neurological
disorders. The present manuscript aimed to discuss various roles of Withania somnifera …
disorders. The present manuscript aimed to discuss various roles of Withania somnifera …
A Review On Huntington Protein: Insight Into Protein Aggregation and Therapeutic Interventions
E Srinivasan, V Ram… - Current Drug …, 2022 - ingentaconnect.com
Huntington's disease (HD) is a distressing, innate neurodegenerative disease that descends
from CAG repeat expansion in the huntingtin gene causing behavioral changes, motor …
from CAG repeat expansion in the huntingtin gene causing behavioral changes, motor …
[HTML][HTML] Natural Medicines and Their Underlying Mechanisms of Prevention and Recovery from Amyloid Β-Induced Axonal Degeneration in Alzheimer's Disease
T Kuboyama, X Yang, C Tohda - International Journal of Molecular …, 2020 - mdpi.com
In Alzheimer's disease (AD), amyloid β (Aβ) induces axonal degeneration, neuronal network
disruption, and memory impairment. Although many candidate drugs to reduce Aβ have …
disruption, and memory impairment. Although many candidate drugs to reduce Aβ have …
[PDF][PDF] Update on the preclinical and clinical assessment of Withania somnifera: from ancient Rasayana to modern perspectives
Abstract The Rasayana plant Withania somnifera (W. somnifera) Dunal, also known as
“Ashwagandha”, has been mentioned in various classical Ayurvedic texts, such as Charaka …
“Ashwagandha”, has been mentioned in various classical Ayurvedic texts, such as Charaka …
Effects of amitriptyline and ashwagandha on the oxidative state and acetylcholine esterase enzyme activities in rats
IR Idrees, GAA Taqa, SKA ALtaaye - Journal of Applied Veterinary …, 2023 - journals.ekb.eg
Amitriptyline has a long history of effectiveness in treating depression. Due to its side effects,
which include oxidative stress and anticholinergic effects, it is used less frequently …
which include oxidative stress and anticholinergic effects, it is used less frequently …