Pannexin channels in ATP release and beyond: an unexpected rendezvous at the endoplasmic reticulum

C D'hondt, R Ponsaerts, H De Smedt, M Vinken… - Cellular signalling, 2011 - Elsevier
The pannexin (Panx) family of proteins, which is co-expressed with connexins (Cxs) in
vertebrates, was found to be a new GJ-forming protein family related to invertebrate …

Vocal fold surface hydration: a review

C Leydon, M Sivasankar, DL Falciglia, C Atkins… - Journal of Voice, 2009 - Elsevier
Vocal fold surface liquid homeostasis contributes to optimal vocal physiology. In this paper
we review emerging evidence that vocal fold surface liquid is maintained in part by salt and …

Bestrophin and TMEM16—Ca2+ activated Cl− channels with different functions

K Kunzelmann, P Kongsuphol, F Aldehni, Y Tian… - Cell calcium, 2009 - Elsevier
In the past, a number of candidates have been proposed to form Ca2+ activated Cl−
currents, but it is only recently that two families of proteins, the bestrophins and the TMEM16 …

Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases

EA Gaillard, P Kota, M Gentzsch, NV Dokholyan… - … -European Journal of …, 2010 - Springer
Mammalian airways are protected from infection by a thin film of airway surface liquid (ASL)
which covers airway epithelial surfaces and acts as a lubricant to keep mucus from adhering …

Metachronal wave formation in a model of pulmonary cilia

SM Mitran - Computers & structures, 2007 - Elsevier
A three-dimensional simulation of the formation of metachronal waves in rows of pulmonary
cilia is presented. The cilia move in a two-layer fluid model. The fluid layer adjacent to the …

Modulation of innate immunity in airway epithelium for host-directed therapy

IT Myszor, GH Gudmundsson - Frontiers in Immunology, 2023 - frontiersin.org
Innate immunity of the mucosal surfaces provides the first-line defense from invading
pathogens and pollutants conferring protection from the external environment. Innate …

17β-Estradiol inhibits Ca2+-dependent homeostasis of airway surface liquid volume in human cystic fibrosis airway epithelia

RD Coakley, H Sun, LA Clunes… - The Journal of …, 2008 - Am Soc Clin Investig
Normal airways homeostatically regulate the volume of airway surface liquid (ASL) through
both cAMP-and Ca2+-dependent regulation of ion and water transport. In cystic fibrosis (CF) …

Emerging concepts and therapies for mucoobstructive lung disease

MA Mall, H Danahay, RC Boucher - Annals of the American …, 2018 - atsjournals.org
A spectrum of intrapulmonary airway diseases, for example, cigarette smoke–induced
bronchitis, cystic fibrosis, primary ciliary dyskinesia, and non–cystic fibrosis bronchiectasis …

Singing lessons for respiratory health: a literature review

RB Goldenberg - Journal of Voice, 2018 - Elsevier
Objective Several studies have explored the role of music and singing as a treatment for
respiratory symptoms. The objective of this paper was to review the current body of literature …

Tgf-beta downregulation of distinct chloride channels in cystic fibrosis-affected epithelia

H Sun, WT Harris, S Kortyka, K Kotha, AJ Ostmann… - PloS one, 2014 - journals.plos.org
Rationale The cystic fibrosis transmembrane conductance regulator (CFTR) and Calcium-
activated Chloride Conductance (CaCC) each play critical roles in maintaining normal …