Immunotherapeutic strategies to induce inflection in the immune response: therapy for cancer and COVID-19
Cancer has agonized the human race for millions of years. The present decade witnesses
biological therapeutics to combat cancer effectively. Cancer Immunotherapy involves the …
biological therapeutics to combat cancer effectively. Cancer Immunotherapy involves the …
Induction of pyroptotic cell death as a potential tool for cancer treatment
Cancer is a complex pathological disease and the existing strategies for introducing
chemotherapeutic agents have restricted potential due to a lack of cancer cell targeting …
chemotherapeutic agents have restricted potential due to a lack of cancer cell targeting …
Paracrine activin B-NF-κB signaling shapes an inflammatory tumor microenvironment in gastric cancer via fibroblast reprogramming
Y Jin, Q Cai, L Wang, J Ji, Y Sun, J Jiang… - Journal of Experimental …, 2023 - Springer
Background Important roles of INHBB in various malignancies are increasingly identified.
The underlying mechanisms in gastric cancer (GC) microenvironment are still greatly …
The underlying mechanisms in gastric cancer (GC) microenvironment are still greatly …
Antitumor effect of luteolin proven by patient‐derived organoids of gastric cancer
X Hao, M Zu, J Ning, X Zhou, Y Gong… - Phytotherapy …, 2023 - Wiley Online Library
Luteolin (Lut) has been shown to inhibit gastric cancer (GC); however, its efficacy compared
to other clinical drugs has not been examined in human samples. This study aimed to …
to other clinical drugs has not been examined in human samples. This study aimed to …
[HTML][HTML] POSTN secretion by extracellular matrix cancer-associated fibroblasts (eCAFs) correlates with poor ICB response via macrophage chemotaxis activation of …
T You, H Tang, W Wu, J Gao, X Li, N Li, X Xu… - Aging and …, 2023 - ncbi.nlm.nih.gov
Immune checkpoint blockade (ICB) therapy has revolutionized cancer treatment, but its
clinical benefit is limited in advanced gastric cancer (GC). Cancer-associated fibroblasts …
clinical benefit is limited in advanced gastric cancer (GC). Cancer-associated fibroblasts …
Identification of prognostic cancer-associated fibroblast markers in luminal breast cancer using weighted gene co-expression network analysis
A Xu, XN Xu, Z Luo, X Huang, RQ Gong… - Frontiers in …, 2023 - frontiersin.org
Background Cancer-associated fibroblasts (CAFs) play a pivotal role in cancer progression
and are known to mediate endocrine and chemotherapy resistance through paracrine …
and are known to mediate endocrine and chemotherapy resistance through paracrine …
A prognostic model of seven immune genes to predict overall survival in childhood acute myeloid leukemia
Y Luo, Y Xu, X Li, X Shi, P Huang… - BioMed Research …, 2022 - Wiley Online Library
Background. Acute myeloid leukemia (AML) is one of the most common hematological
malignancies and accounts for about 20% of childhood leukemias. Currently …
malignancies and accounts for about 20% of childhood leukemias. Currently …
Mechanisms and biomarkers of immune-related adverse events in gastric cancer
P Ding, P Liu, L Meng, Q Zhao - European Journal of Medical Research, 2023 - Springer
Abstract Immune-checkpoint inhibitors (ICIs), different from traditional cancer treatment
models, have shown unprecedented anti-tumor effects in the past decade, greatly improving …
models, have shown unprecedented anti-tumor effects in the past decade, greatly improving …
Molecular Networks of Platinum Drugs and Their Interaction with microRNAs in Cancer
S Tanabe, E Boonstra, T Hong, S Quader, R Ono… - Genes, 2023 - mdpi.com
The precise mechanism of resistance to anti-cancer drugs such as platinum drugs is not fully
revealed. To reveal the mechanism of drug resistance, the molecular networks of anti-cancer …
revealed. To reveal the mechanism of drug resistance, the molecular networks of anti-cancer …
[HTML][HTML] Identification of a novel inflammatory-related gene signature to evaluate the prognosis of gastric cancer patients
JL Hu, MJ Huang, H Halina, K Qiao… - World Journal of …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Gastric cancer (GC) is a highly aggressive malignancy with a
heterogeneous nature, which makes prognosis prediction and treatment determination …
heterogeneous nature, which makes prognosis prediction and treatment determination …