The active form of vitamin D 3, 1, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3), is primarily
known as a key regulator of calcium and phosphate homeostasis. It exerts its biological …

Simple Summary The effect of vitamin D3 on the development of breast cancer (favorable,
ineffective, or even unfavorable) depends on many factors, such as age, menopausal status …

The use of doxorubicin (Dox) in the treatment of breast cancer negatively affects the
intestines and other tissues. Many studies have proven that probiotics and vitamin D3 have …

Simple Summary This study, which was conducted in healthy mice and mice bearing three
mouse mammary gland cancers—4T1, 67NR, and E0771—showed that the divergent …

Our research found that vitamin D3 (VD3) treatment increased lung metastasis in mice with
4T1 murine breast cancer (BC). This study aims to investigate the impact of VD3 on the …

Simple Summary In this study, we stimulated bone marrow-derived macrophages to M0, M1,
and M2 subtypes, with or without calcitriol, or with or without 4T1 (metastatic), 67NR (non …

Abstract Background Cancer-associated fibroblasts (CAFs) play an important role in the
tumor microenvironment. Despite the well-known in vitro antitumoral effect of vitamin D3 …

Background Myotonic dystrophy type 1 (DM1), one of the most common forms of adult-onset
muscular dystrophy, is caused by abnormally expanded CTG repeats in the 3′ untranslated …

Many clinical studies have reported that patients diagnosed with cancer will suffer from
sleep disturbance during their clinical process, especially among lung cancer patients, and …

1, 25-Dihydroxycholecalciferol, the hormonally active vitamin D3 metabolite, is known to
exhibit therapeutic effects against breast cancer, mainly by lowering the expression of …