[HTML][HTML] Recent Advances of Biosensors for Detection of Multiple Antibiotics

N Lu, J Chen, Z Rao, B Guo, Y Xu - Biosensors, 2023 - mdpi.com
The abuse of antibiotics has caused a serious threat to human life and health. It is urgent to
develop sensors that can detect multiple antibiotics quickly and efficiently. Biosensors are …

[HTML][HTML] The combination of antibiotic and non-antibiotic compounds improves antibiotic efficacy against multidrug-resistant bacteria

G Xiao, J Li, Z Sun - International Journal of Molecular Sciences, 2023 - mdpi.com
Bacterial antibiotic resistance, especially the emergence of multidrug-resistant (MDR)
strains, urgently requires the development of effective treatment strategies. It is always of …

Challenges and advances in antimicrobial peptide development

KBS de Oliveira, ML Leite, VA Cunha, NB da Cunha… - Drug Discovery …, 2023 - Elsevier
Microbial resistance is a major concern for public health worldwide, mainly because of the
inappropriate use of antimicrobials. In this scenario, antimicrobial peptides (AMPs) have …

[HTML][HTML] Anti-Pseudomonas aeruginosa Vaccines and Therapies: An Assessment of Clinical Trials

MM Elmassry, JA Colmer-Hamood, J Kopel… - Microorganisms, 2023 - mdpi.com
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that causes high
morbidity and mortality in cystic fibrosis (CF) and immunocompromised patients, including …

[HTML][HTML] Age of Antibiotic Resistance in MDR/XDR Clinical Pathogen of Pseudomonas aeruginosa

A Kothari, R Kherdekar, V Mago, M Uniyal, G Mamgain… - Pharmaceuticals, 2023 - mdpi.com
Antibiotic resistance in Pseudomonas aeruginosa remains one of the most challenging
phenomena of everyday medical science. The universal spread of high-risk clones of …

[HTML][HTML] Complementary activities of host defence peptides and antibiotics in combating antimicrobial resistant bacteria

PR Lennard, PS Hiemstra, PH Nibbering - Antibiotics, 2023 - mdpi.com
Due to their ability to eliminate antimicrobial resistant (AMR) bacteria and to modulate the
immune response, host defence peptides (HDPs) hold great promise for the clinical …

Current and emerging strategies to curb antibiotic-resistant urinary tract infections

A Simoni, L Schwartz, GY Junquera, CB Ching… - Nature Reviews …, 2024 - nature.com
Rising rates of antibiotic resistance in uropathogenic bacteria compromise patient outcomes
and prolong hospital stays. Consequently, new strategies are needed to prevent and control …

Phage-Encoded Antimicrobial Peptide gp28 Demonstrates LL-37-Like Antimicrobial Activity Against Multidrug-Resistant Pseudomonas aeruginosa

RC Wilkinson, NE Thomas, A Bhatti, MR Burton… - PHAGE, 2024 - liebertpub.com
Background: Pseudomonas aeruginosa (P. aeruginosa) is a gram-negative bacterial
pathogen commonly associated with nosocomial infections. Treatment of P. aeruginosa …

Evaluation of the Anti-biofilm Efficacy of Kyotorphin Derivatives and Biosafety Assessment: In Vitro and In Vivo Investigations Targeting Bacterial and Fungal …

ICS Carvalho, F da Silva Seiffert Simões… - International Journal of …, 2024 - Springer
Abstract Kyotorphin (KTP) dipeptide (l-Tyrosine-l-Arginine) and their derivatives possess a
multitude of functions, qualifying them as" multifunctional peptides." Considering the …

[HTML][HTML] Galleria Mellonella Larvae as an Model for Testing Microbial Pathogenicity

D Gniazdo, W Sasal, A Omelaniuk, W Brudz… - Advancements of …, 2023 - sciendo.com
The larvae of the insect Galleria mellonella have gained wide acceptance as an in vivo
model for the study of virulence in Gramnegative and Gram-positive bacteria and fungi …