Hypoxia is a known feature of solid tumors and a critical promoter of tumor hallmarks.
Hypoxia influences tumor immunity in a way favoring immune evasion and resistance …

Hypoxia is a common phenomenon in most malignant tumors, especially in pancreatic
cancer (PC). Hypoxia is the result of unlimited tumor growth and plays an active role in …

Pancreatic cancer (PC) is the most hypoxic cancer type among solid tumors. The dynamic
changes of RNA N6-methyl-adenosine (m6A) contribute to tumor cells adaption to hypoxic …

Pancreatic ductal adenocarcinoma (PDAC) is characterized by hypoxic tumor
microenvironment (TME), which aids tumor progression, drug resistance, and immune …

Accurate diagnosis of tumors and predicting the therapeutic responses are highly
demanded in the clinic to improve the treatment efficacy and survival rates. Since hypoxia …

We aim to construct a hypoxia-and immune-associated risk score model to predict the
prognosis of patients with pancreatic ductal adenocarcinoma (PDAC). By unsupervised …

Pancreatic stellate cells (PSCs) are important components of the tumor microenvironment in
pancreatic cancer (PC) and contribute to its development and metastasis through …

Pancreatic ductal adenocarcinoma (PDAC) represents a challenge for a multidisciplinary
oncology team. Diagnosis of PDAC remains challenging due to overlapping imaging …

Simple Summary PDAC is one of the most malignant tumors and its treatment, whether
surgery or chemotherapy, has shown poor results. Resistance to gemcitabine and other …

Recent studies reveal a critical role of tumor cell-released extracellular vesicles (EVs) in
pancreatic cancer (PC) progression. However, driver genes that direct EV function, the EV …