伴del (5q) 的骨髓增生异常综合征的分子生物学研究进展

年青, 王利 - 重庆医科大学学报, 2015 - cqvip.com
骨髓增生异常综合征(myelodysplastic syndromes, MDS) 是一组起源于多能造血干/祖细胞的异
质性恶性血液病, 其发病机制尚不清楚. 5 号染色体长臂缺失是其最常见的分子生物学改变之一 …

SPARC 对房水流出道作用的研究进展

丛琳, 张宇燕 - 国际眼科纵览, 2015 - cqvip.com
原发性开角型青光眼(primary open-angle glaucoma, POAG) 发病机制中有多种分子及信号
通路参与, 但确切的发病机制尚不清楚. 富含半胱氨酸的分泌型酸性蛋白(secreted protein …

SPARC 基因过表达对SKM-1 细胞凋亡的影响

年青, 魏春梅, 黄婧, 但春莉, 肖青, 杨泽松, 王利 - 中国细胞生物学学报, 2014 - cqvip.com
构建SPARc 基因过表达载体, 转染人骨髓增生异常综合征(myelodysplastic syndrome, MDS)-
u/胞系SKM-1 细胞, 探讨SPARc 基因过表达对! &MDS 细胞系SKM 一1 细胞凋亡的影响. XpcD …

Aqueous Humor Outflow

G Akiyama, T Bogarin, S Saraswathy… - … and Hydrodynamics of the …, 2021 - Springer
Aqueous humor outflow (AHO) is important for supporting normal eye physiology and vision.
Altered AHO occurs in glaucoma because increased AHO resistance leads to increased …

Plant-derived angiogenin fusion protein's cytoprotective effect on trabecular meshwork damage induced by Benzalkonium chloride in mice

JH Jeong, SJ Lee, K Ko, JH Lee, J Lyu, MH Park… - PeerJ, 2020 - peerj.com
Background Benzalkonium chloride (BAK), commonly used in glaucoma treatment, is an eye
drop preservative with dose-dependent toxicity. Previous studies have observed the multi …

Molecular differences in segmental regions of the trabecular meshwork

JA Vranka, TS Acott - Glaucoma Research and Clinical …, 2016 - books.google.com
Aqueous humor outflow has long been known to be segmental in nature with regions of
relatively high, intermediate, and low aqueous outflow around the circumference of the eye …

Schlemm's Canal: The Outflow “Vessel”

J Jabłońska, K Lewczuk, M Rękas - … : Intraocular Pressure and …, 2016 - books.google.com
The aim of this chapter is to review the knowledge about the aqueous outflow through
Schlemm's canal. Morphology of this canal and aqueous humor pathways from the anterior …

5. Gene expression sequence alteration and impaired proteolysis: are they contributory in glaucoma?

B Freedman, H Sandler, SM Iverson… - … Advances: 2020 to …, 2020 - books.google.com
Purpose: To determine whether expression sequence becomes detrimental for bacteria. We
speculate that of extracellular matrix (ECM) proteins/cochlin is altered expression sequence …

Methods of treating glaucoma using amp-activated protein kinase (ampk) activators

DJ Rhee, G Villarreal Jr, A Chatterjee… - US Patent App. 15 …, 2017 - Google Patents
BACKGROUND 0004 Glaucoma is a leading cause of irreversible blind ness.'Elevated
intraocular pressure (IOP) in eyes with primary open-angle glaucoma (POAG) is caused by …

[HTML][HTML] Aqueous Humor Outflow Assessment

X Xie, G Akiyama, T Bogarin… - Asia-Pacific journal of …, 2019 - ncbi.nlm.nih.gov
In the past decade, many new pharmacological and surgical treatments have become
available to lower intraocular pressure (IOP) for glaucoma. The majority of these options …