The morbidity associated with neurodegenerative diseases (NDs) is increasing, posing a
threat to the mental and physical quality of life of humans. The crucial effect of microbiota on …

Abstract Nuclear Factor-Erythroid Factor 2 (Nrf2) is an important transcription factor that
regulates the expression of large number of genes in healthy and disease states. Nrf2 is …

Use of glucagon-like peptide-1 receptor agonist or dipeptidyl peptidase 4 inhibitor has been
shown to lower the incidence of Parkinson's disease in patients with diabetes mellitus …

Rare mutations in the mitochondrial protein coiled-coil-helix-coiled-coil-helix domain
containing 2 (CHCHD2) are associated with Parkinson's disease (PD) and other Lewy body …

Parkinson's disease (PD) is one of the major neurodegenerative diseases (ND) which
presents a progressive neurodegeneration characterized by loss of dopamine in the …

Background Neuroinflammation has been widely accepted as a cause of the degenerative
process. Increasing interest has been devoted to developing intervening therapeutics for …

Parkinson's disease (PD) is the most common brain motor disorder, characterized by a
substantial loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) …

The old people often suffer from circadian rhythm disturbances, which in turn accelerate
aging. Many aging-related degenerative diseases such as Alzheimer's disease, Parkinson's …

Parkinson's disease (PD) is a progressive neurodegenerative disorder with a complex
etiology. Neuroinflammation and oxidative stress are important factors driving the …

Endogenous and exogenous neurotoxins are important factors leading to
neurodegenerative diseases. In the 1980s, the discovery that 1-methyl-4-phenyl-1, 2, 3, 6 …