[HTML][HTML] Characterization of neurobehavioral pattern in a zebrafish 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced model: A 96-hour behavioral study
Parkinson's disease (PD) is the most common brain motor disorder, characterized by a
substantial loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) …
substantial loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) …
[HTML][HTML] Neurotoxicity and underlying mechanisms of endogenous neurotoxins
Endogenous and exogenous neurotoxins are important factors leading to
neurodegenerative diseases. In the 1980s, the discovery that 1-methyl-4-phenyl-1, 2, 3, 6 …
neurodegenerative diseases. In the 1980s, the discovery that 1-methyl-4-phenyl-1, 2, 3, 6 …
[HTML][HTML] Neuroprotective effects of the DPP4 inhibitor vildagliptin in in vivo and in vitro models of Parkinson's disease
Parkinson's disease (PD) is characterized by loss of dopaminergic neurons in the substantia
nigra pars compacta (SNpc) of the midbrain. Restoration of nigrostriatal dopamine neurons …
nigra pars compacta (SNpc) of the midbrain. Restoration of nigrostriatal dopamine neurons …
[HTML][HTML] Synucleinopathy in amyotrophic lateral sclerosis: a potential avenue for antisense therapeutics?
Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease
classified as both a neurodegenerative and neuromuscular disorder. With a complex …
classified as both a neurodegenerative and neuromuscular disorder. With a complex …
[HTML][HTML] Hydrogen sulfide (H2S) signaling as a protective mechanism against endogenous and exogenous neurotoxicants
In view of the significant role of H 2 S in brain functioning, it is proposed that H2S may also
possess protective effects against adverse effects of neurotoxicants. Therefore, the objective …
possess protective effects against adverse effects of neurotoxicants. Therefore, the objective …
Deciphering clock genes as emerging targets against aging
Y Zhu, Y Liu, G Escames, Z Yang, H Zhao, L Qian… - Ageing Research …, 2022 - Elsevier
The old people often suffer from circadian rhythm disturbances, which in turn accelerate
aging. Many aging-related degenerative diseases such as Alzheimer's disease, Parkinson's …
aging. Many aging-related degenerative diseases such as Alzheimer's disease, Parkinson's …
Amelioration of Parkinson's disease by pharmacological inhibition and knockdown of redox sensitive TRPC5 channels: Focus on mitochondrial health
Aims Transient receptor potential canonical 5 (TRPC5) channels are redox-sensitive cation-
permeable channels involved in temperature and mechanical sensation. Increased …
permeable channels involved in temperature and mechanical sensation. Increased …
[HTML][HTML] Elucidating the neuroprotective role of PPARs in Parkinson's disease: a neoteric and prospective target
One of the utmost frequently emerging neurodegenerative diseases, Parkinson's disease
(PD) must be comprehended through the forfeit of dopamine (DA)-generating nerve cells in …
(PD) must be comprehended through the forfeit of dopamine (DA)-generating nerve cells in …
[HTML][HTML] Epimedin B exerts neuroprotective effect against MPTP-induced mouse model of Parkinson's disease: GPER as a potential target
M Zhang, ZF Hu, XL Dong, WF Chen - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Mitochondrial dysfunction and oxidative stress play important roles in the
neuropathogenesis of Parkinson's disease (PD). Epimedin B, the second highest active …
neuropathogenesis of Parkinson's disease (PD). Epimedin B, the second highest active …
ncRNAs and Their Impact on Dopaminergic Neurons: Autophagy Pathways in Parkinson's Disease
Parkinson's Disease (PD) is a complex neurological illness that causes severe motor and
non-motor symptoms due to a gradual loss of dopaminergic neurons in the substantia nigra …
non-motor symptoms due to a gradual loss of dopaminergic neurons in the substantia nigra …