Ukgansan Protects Dopaminergic Neurons against MPTP‐Induced Neurotoxicity via the Nurr1 Signaling Pathway

IC Chae, JH Jang, IC Seol, YS Kim… - Evidence‐Based …, 2022 - Wiley Online Library
Nuclear receptor‐related 1 protein (Nurr1) is a nuclear hormone receptor that protects
dopaminergic neurons and is a promising therapeutic target for Parkinson's disease (PD) …

Secretory Clusterin Inhibits Dopamine Neuron Apoptosis in MPTP Mice by Preserving Autophagy Activity

D Zhu, S Zhang, X Wang, C Xiao, G Cui, X Yang - Neuroscience, 2024 - Elsevier
Secretory clusterin (sCLU) plays an important role in the research progress of nervous
system diseases. However, the physiological function of sCLU in Parkinson's disease (PD) …

Oral administration of sophoricoside (SOP) inhibits neuronal damage and neuroinflammation to curb neurodegeneration in Parkinson's disease

H Wang, D He, Z Li, X Gao, S Yang, M Cui, B Ye… - Chemico-Biological …, 2023 - Elsevier
Neuronal apoptosis and neuroinflammation are key factors involved in the pathological
changes of Parkinson's disease (PD). Sophoricoside (SOP) has shown anti-inflammatory …

Early B Cell Factor 3 (EBF3) attenuates Parkinson's disease through directly regulating contactin-associated protein-like 4 (CNTNAP4) transcription: An experimental …

W Hu, M Wang, G Sun, L Zhang, H Lu - Cellular Signalling, 2024 - Elsevier
Parkinson's disease (PD) is a gradually debilitating neurodegenerative syndrome. Here, we
analyzed GSE7621 chip data obtained from the Gene Expression Omnibus (GEO) database …

Cytarabine prevents neuronal damage by enhancing AMPK to stimulate PINK1/Parkin-involved mitophagy In Parkinson's disease model

L Li, Y Zhang, Z Chen, C Xu, Z Xu, H Pei… - European Journal of …, 2024 - Elsevier
Parkinson's disease (PD) is a common age-related neurodegenerative disorder, which may
be largely due to the mitochondrial dysfunction and impaired mitophagy. Thus, it is of great …

Rotenone-induced PINK1/Parkin-mediated mitophagy: establishing a silkworm model for Parkinson's disease potential

H Zhang, J Yang, Y Guo, P Lü, X Gong… - Frontiers in Molecular …, 2024 - frontiersin.org
Parkinson's disease (PD), ranking as the second most prevalent neurodegenerative
disorder globally, presents a pressing need for innovative animal models to deepen our …

[HTML][HTML] Neuroprotective effect of rice bran enzymatic extract-supplemented diets in a murine model of Parkinsońs disease

E Gavilán, A Flores, A Castaño, L Martin-Presas… - Journal of Functional …, 2024 - Elsevier
Neurodegenerative disorders such as Parkinson's disease, present a global health concern
with limited therapeutic options. In this context, dietary interventions have emerged as a …

Nigrostriatal Inflammation Is Associated with Nonmotor Symptoms in an Experimental Model of Prodromal Parkinson's Disease

B da Silva Oliveira, EC de Brito Toscano, LKS Abreu… - Neuroscience, 2024 - Elsevier
Recent evidence has supported a pathogenic role for neuroinflammation in Parkinson's
disease (PD). Inflammatory response has been associated with symptoms and subtypes of …

Mitolysosome exocytosis: a novel mitochondrial quality control pathway linked with parkinsonism-like symptoms

F Bao, L Zhou, J Xiao, X Liu - Biochemical Society Transactions, 2022 - portlandpress.com
Quality control of mitochondria is essential for their homeostasis and function. Light chain 3
(LC3) associated autophagosomes-mediated mitophagy represents a canonical …

Role of Nutraceuticals and Physical Activity in Parkinson's Disease Risk and Lifestyle Management

P Wal, H Vig, A Wal, S Rathore, SS Pandey… - Current Aging …, 2023 - ingentaconnect.com
Background: Parkinson's disease is a complicated, gradually progressive neurological
illness characterized by locomotor and non-motor symptomatology that impedes daily …