RNA-seq reveals role of cell-cycle regulating genes in the pathogenicity of a field very virulent infectious bursal disease virus

J Chen, W Wang, S Li, Z Wang, W Zuo… - Frontiers in Veterinary …, 2024 - frontiersin.org
Infectious bursal disease virus (IBDV) infection causes highly contagious and
immunosuppressive disease in poultry. The thymus, serving as the primary organ for T cell …

[HTML][HTML] Pigeon MDA5 inhibits viral replication by triggering antiviral innate immunity

Q Shao, F Fu, P Zhu, X Yu, J Wang, Z Wang, J Ma… - Poultry Science, 2023 - Elsevier
Pigeons are considered less susceptible, and display few or no clinical signs to infection
with avian influenza virus (AIV). Melanoma differentiation-associated gene 5 (MDA5), an …

[HTML][HTML] Pigeon RIG-I function in innate immunity against H9N2 IAV and IBDV

W Xu, Q Shao, Y Zang, Q Guo, Y Zhang, Z Li - Viruses, 2015 - mdpi.com
Retinoic acid-inducible gene I (RIG-I), a cytosolic pattern recognition receptor (PRR), can
sense various RNA viruses, including the avian influenza virus (AIV) and infectious bursal …

p53 mediated IFN-β signaling to affect viral replication upon TGEV infection

L Ding, J Li, W Li, Z Fang, N Li, Q Guo, H Qu… - Veterinary …, 2018 - Elsevier
TGEV can induce IFN-β production, which in turn plays a vital role in host antiviral immune
responses. Our previous studies showed that TGEV infection activated p53 signaling to …

Role of microRNA-34b-5p in cancer and injury: how does it work?

X Bai, L Zheng, Y Xu, Y Liang, D Li - Cancer Cell International, 2022 - Springer
MicroRNAs (miRNAs or miRs) are a class of noncoding single-stranded RNAs that can
regulate gene expression by binding to the untranslated sequences at the 3'end of …

Genetic responses of inbred chicken lines illustrate importance of eIF2 family and immune-related genes in resistance to Newcastle disease virus

AP Del Vesco, MG Kaiser, MS Monson, H Zhou… - Scientific reports, 2020 - nature.com
Newcastle disease virus (NDV) replication depends on the translation machinery of the host
cell; therefore, the eukaryotic translation initiation factor 2 (eIF2) gene family is a likely …

Transcription profiles of the responses of chicken bursae of Fabricius to IBDV in different timing phases

C Ou, Q Wang, Y Zhang, W Kong, S Zhang, Y Yu, J Ma… - Virology journal, 2017 - Springer
Background Infectious bursal disease virus (IBDV) infection causes immunosuppression in
chickens and increases their susceptibility to secondary infections. To explore the interaction …

Promoter structures and differential responses to viral and non-viral inducers of chicken melanoma differentiation-associated gene 5

WX Zhang, EW Zuo, Y He, DY Chen, X Long… - Molecular …, 2016 - Elsevier
Melanoma differentiation-associated gene 5 (MDA5) is a member of the retinoic acid-
inducible gene I (RIG-I)-like receptors (RLRs) family and plays a pivotal role in the anti-viral …

[HTML][HTML] The down-regulation of casein kinase 1 alpha as a host defense response against infectious bursal disease virus infection

L Zhang, H Li, Y Chen, X Gao, Z Lu, L Gao, Y Wang… - Virology, 2017 - Elsevier
Infectious bursal disease virus (IBDV) is an important immunosuppressive virus of chickens.
Although the gene functions of IBDV have been well characterized, the host responses …

Functional analysis of duck, goose, and ostrich 2′-5′-oligoadenylate synthetase

HT Tag-EL-Din-Hassan, M Morimatsu, T Agui - Infection, Genetics and …, 2018 - Elsevier
Up-to-date the flavivirus infection in avian taxa is not clearly defined. Several reports have
demonstrated that many viruses belonging to Flaviviridae may cause diseases in poultry …