Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

Most antidepressants change sleep; in particular, they alter the physiological patterns of
sleep stages recorded overnight with EEG and other physiological measures. These effects …

Sleep problems are frequently associated with the principal diagnostic criteria for many
mental disorders. Alterations in the sleep of depressive patients are of high clinical …

Abstract Study Objectives: Rapid eye movement (REM) sleep behavior disorder (RBD) is
generally observed in older men and in individuals with specific neurologic diseases. There …

Although major depressive disorder is primarily considered a mood disorder, depressed
patients commonly present with clinically significant cognitive dysfunction that may add to …

Cannabidiol (CBD) is a component of Cannabis sativa that has a broad spectrum of
potential therapeutic effects in neuropsychiatric and other disorders. However, few studies …

Depressed patients often report sleep problems, which usually include difficulties with
initiation and maintenance of sleep, as well as poor subjective quality of sleep. Such reports …

Background Arousal and sleep represent basic domains of behavior, and alterations are of
high clinical importance. Objective/hypothesis The aim of this study was to further elucidate …

According to the hyperarousal model, insomnia is characterised by increased arousal in the
cortical, cognitive, and physiological domains. However, the interaction between these …

The selective serotonin reuptake inhibitor (SSRI) Prozac®(fluoxetine) is the only registered
antidepressant to treat depression in children and adolescents. Yet, while the safety of …