Infection, autoimmunity, and cancer are principal human health challenges of the 21 st
century. Often regarded as distinct ends of the immunological spectrum, recent studies hint …

Introduction The etiology of multiple sclerosis (MS) remains unknown. Pathogenesis likely
relies on a complex interaction between multiple environmental, genetic, and behavioral risk …

Natural killer cells that target autoimmune cells linked with protection against multiple
sclerosis | Nature Reviews Immunology Skip to main content Thank you for visiting nature.com …

Intracellular trafficking involves an intricate machinery of motor complexes including the
dynein complex to shuttle cargo for autophagolysosomal degradation. Deficiency in dynein …

In a recent study published in Cell, Vietzen and colleagues discovered the novel role of
natural killer (NK) cells and EBV-specific CD8+ T cell response in controlling EBV-inducing …

Background To study the shared genetic structure between autoimmune diseases and B-cell
acute lymphoblastic leukemia (B-ALL) and identify the shared risk loci and genes and …

Encounters with pathogens and other molecules can imprint long-lasting effects on our
immune system, influencing future physiological outcomes. Given the wide range of …

Background and Objectives The role of B cells in the pathogenic events leading to relapsing
multiple sclerosis (R-MS) has only been recently elucidated. A pivotal step in defining this …

Introduction Body fluid markers could be helpful to predict the conversion into clinically
definite multiple sclerosis (MS) in people with a first demyelinating event of the central …

Background: Previous investigations into multiple sclerosis (MS) risk factors predominantly
relied on retrospective studies, which do not consider different follow-up times and assume a …