Key viral adaptations preceding the AIDS pandemic
D Sauter, F Kirchhoff - Cell host & microbe, 2019 - cell.com
HIV, the causative agent of AIDS, has a complex evolutionary history involving several cross-
species transmissions and recombination events as well as changes in the repertoire and …
species transmissions and recombination events as well as changes in the repertoire and …
Non-M variants of human immunodeficiency virus type 1
T Mourez, F Simon, JC Plantier - Clinical microbiology reviews, 2013 - Am Soc Microbiol
The AIDS pandemic that started in the early 1980s is due to human immunodeficiency virus
type 1 (HIV-1) group M (HIV-M), but apart from this major group, many divergent variants …
type 1 (HIV-1) group M (HIV-M), but apart from this major group, many divergent variants …
The potency of Nef-mediated SERINC5 antagonism correlates with the prevalence of primate lentiviruses in the wild
The cellular factor serine incorporator 5 (SERINC5) impairs HIV-1 infectivity but is
antagonized by the viral Nef protein. We analyzed the anti-SERINC5 activity of Nef proteins …
antagonized by the viral Nef protein. We analyzed the anti-SERINC5 activity of Nef proteins …
Host restriction factors in retroviral infection: promises in virus-host interaction
YH Zheng, KT Jeang, K Tokunaga - Retrovirology, 2012 - Springer
Retroviruses have an intricate life cycle. There is much to be learned from studying retrovirus-
host interactions. Among retroviruses, the primate lentiviruses have one of the more complex …
host interactions. Among retroviruses, the primate lentiviruses have one of the more complex …
The antiviral activities of tetherin
SJD Neil - Intrinsic Immunity, 2013 - Springer
Abstract Tetherin (BST2/CD317) has emerged as a key host cell defense molecule,
inhibiting the release and spread of diverse enveloped virions from infected cells. In this …
inhibiting the release and spread of diverse enveloped virions from infected cells. In this …
Nef proteins of epidemic HIV-1 group O strains antagonize human tetherin
Most simian immunodeficiency viruses use their Nef protein to antagonize the host
restriction factor tetherin. A deletion in human tetherin confers Nef resistance, representing a …
restriction factor tetherin. A deletion in human tetherin confers Nef resistance, representing a …
The role of BST‐2/Tetherin in host protection and disease manifestation
WD Mahauad‐Fernandez… - … inflammation and disease, 2016 - Wiley Online Library
Host cells respond to viral infections by activating immune response genes that are not only
involved in inflammation, but may also predispose cells to cancerous transformation. One …
involved in inflammation, but may also predispose cells to cancerous transformation. One …
Eastern chimpanzees, but not bonobos, represent a simian immunodeficiency virus reservoir
Y Li, JB Ndjango, GH Learn, MA Ramirez… - Journal of …, 2012 - Am Soc Microbiol
Chimpanzees in west central Africa (Pan troglodytes troglodytes) are endemically infected
with simian immunodeficiency viruses (SIVcpz Ptt) that have crossed the species barrier to …
with simian immunodeficiency viruses (SIVcpz Ptt) that have crossed the species barrier to …
Vpu protein: The viroporin encoded by HIV-1
ME González - Viruses, 2015 - mdpi.com
Viral protein U (Vpu) is a lentiviral viroporin encoded by human immunodeficiency virus type
1 (HIV-1) and some simian immunodeficiency virus (SIV) strains. This small protein of 81 …
1 (HIV-1) and some simian immunodeficiency virus (SIV) strains. This small protein of 81 …
Multilayered and versatile inhibition of cellular antiviral factors by HIV and SIV accessory proteins
D Sauter, F Kirchhoff - Cytokine & growth factor reviews, 2018 - Elsevier
HIV-1, the main causative agent of AIDS, and related primate lentiviruses show a striking
ability to efficiently replicate throughout the lifetime of an infected host. In addition to their …
ability to efficiently replicate throughout the lifetime of an infected host. In addition to their …