Maternal immune activation and neuroinflammation in human neurodevelopmental disorders

VX Han, S Patel, HF Jones, RC Dale - Nature Reviews Neurology, 2021 - nature.com
Maternal health during pregnancy plays a major role in shaping health and disease risks in
the offspring. The maternal immune activation hypothesis proposes that inflammatory …

Nrf2 and oxidative stress: A general overview of mechanisms and implications in human disease

V Ngo, ML Duennwald - Antioxidants, 2022 - mdpi.com
Organisms are continually exposed to exogenous and endogenous sources of reactive
oxygen species (ROS) and other oxidants that have both beneficial and deleterious effects …

[HTML][HTML] Chronic inflammation in the etiology of disease across the life span

D Furman, J Campisi, E Verdin, P Carrera-Bastos… - Nature medicine, 2019 - nature.com
Although intermittent increases in inflammation are critical for survival during physical injury
and infection, recent research has revealed that certain social, environmental and lifestyle …

Dietary inflammatory index and non-communicable disease risk: a narrative review

CM Phillips, LW Chen, B Heude, JY Bernard… - Nutrients, 2019 - mdpi.com
There are over 1,000,000 publications on diet and health and over 480,000 references on
inflammation in the National Library of Medicine database. In addition, there have now been …

Dual synergistic inhibition of COX and LOX by potential chemicals from Indian daily spices investigated through detailed computational studies

M Rudrapal, WA Eltayeb, G Rakshit, AA El-Arabey… - Scientific reports, 2023 - nature.com
Abstract Cyclooxygenase (COX) and Lipoxygenase (LOX) are essential enzymes for
arachidonic acid (AA) to eicosanoids conversion. These AA-derived eicosanoids are …

Epigenetic signatures underlying inflammation: An interplay of nutrition, physical activity, metabolic diseases, and environmental factors for personalized nutrition

O Ramos-Lopez, FI Milagro, JI Riezu-Boj… - Inflammation …, 2021 - Springer
Aim and objective Emerging translational evidence suggests that epigenetic alterations
(DNA methylation, miRNA expression, and histone modifications) occur after external stimuli …

Aging, inflammaging and immunosenescence as risk factors of severe COVID-19

AM Tizazu, HM Mengist, G Demeke - Immunity & Ageing, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused
by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is …

Inflammation and oxidative stress in chronic kidney disease and dialysis patients

T Ebert, O Neytchev, A Witasp… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Chronic kidney disease (CKD) can be regarded as a burden of lifestyle
disease that shares common underpinning features and risk factors with the aging process; …

[HTML][HTML] Pinostrobin ameliorates lipopolysaccharide (LPS)-induced inflammation and endotoxemia by inhibiting LPS binding to the TLR4/MD2 complex

AMGK Athapaththu, KT Lee, MHD Kavinda… - Biomedicine & …, 2022 - Elsevier
Pinostrobin is a natural flavonoid with valuable pharmacological properties, including anti-
cancer, anti-viral, and anti-oxidant activities. However, the anti-inflammatory effects of …

Associations of dietary intake on biological markers of inflammation in children and adolescents: a systematic review

M Bujtor, AI Turner, SJ Torres, L Esteban-Gonzalo… - Nutrients, 2021 - mdpi.com
Background: In children and adolescents, chronic low-grade inflammation has been
implicated in the pathogenesis of co-and multi-morbid conditions to mental health disorders …