The cholinergic anti-inflammatory pathway in humans: State-of-the-art review and future directions

NV Alen - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
The parasympathetic nervous system modulates inflammation through efferent vagus nerve
signaling. Tracey (2002) termed this process as the cholinergic anti-inflammatory pathway …

[HTML][HTML] The Microbiota–Gut–Brain Axis: Psychoneuroimmunological Insights

G Marano, M Mazza, FM Lisci, M Ciliberto, G Traversi… - Nutrients, 2023 - mdpi.com
There is growing interest in the role that the intestinal microbiota and the related
autoimmune processes may have in the genesis and presentation of some psychiatric …

[HTML][HTML] Key role of the gut–microbiota–brain axis via the subdiaphragmatic vagus nerve in demyelination of the cuprizone-treated mouse brain

X Wang, A Eguchi, Y Yang, L Chang, X Wan… - Neurobiology of …, 2023 - Elsevier
Multiple sclerosis (MS) is the most common demyelinating disease that attacks the central
nervous system. Dietary intake of cuprizone (CPZ) produces demyelination resembling that …

[HTML][HTML] Vagus nerve stimulation alleviated cerebral ischemia and reperfusion injury in rats by inhibiting pyroptosis via α7 nicotinic acetylcholine receptor

H Tang, J Li, Q Zhou, S Li, C Xie, L Niu, J Ma… - Cell death discovery, 2022 - nature.com
Cumulative evidence suggests that pyroptosis, a new sort of programmed cell death, is
closely related to cerebral ischemia/reperfusion (I/R) injury. Our previous studies have …

[HTML][HTML] The potential of flavonoids and flavonoid metabolites in the treatment of neurodegenerative pathology in disorders of cognitive decline

J Melrose - Antioxidants, 2023 - mdpi.com
Flavonoids are a biodiverse family of dietary compounds that have antioxidant, anti-
inflammatory, antiviral, and antibacterial cell protective profiles. They have received …

[HTML][HTML] Transcranial focused ultrasound neuromodulation: a review of the excitatory and inhibitory effects on brain activity in human and animals

T Zhang, N Pan, Y Wang, C Liu, S Hu - Frontiers in Human …, 2021 - frontiersin.org
Non-invasive neuromodulation technology is important for the treatment of brain diseases.
The effects of focused ultrasound on neuronal activity have been investigated since the …

[HTML][HTML] The multibranched nerve: vagal function beyond heart rate variability

JM Karemaker - Biological Psychology, 2022 - Elsevier
This paper reviews the many functions of the vagus nerve, to understand how they interact in
daily life and what might be accomplished by therapeutical electrical stimulation. A short …

[HTML][HTML] Neuroimmunomodulation of vagus nerve stimulation and the therapeutic implications

YT Fang, YT Lin, WL Tseng, P Tseng… - Frontiers in Aging …, 2023 - frontiersin.org
Vagus nerve stimulation (VNS) is a technology that provides electrical stimulation to the
cervical vagus nerve and can be applied in the treatment of a wide variety of …

Effects of spleen nerve denervation on depression–like phenotype, systemic inflammation, and abnormal composition of gut microbiota in mice after administration of …

L Ma, J Zhang, Y Fujita, H Shinno-Hashimoto… - Journal of Affective …, 2022 - Elsevier
Background Accumulating evidence suggests the role of brain–spleen axis as well as brain–
gut–microbiota axis in inflammation-related depression. The spleen mediates anti …

[HTML][HTML] Mitochondrial quality control in the brain: The physiological and pathological roles

X Shen, P Sun, H Zhang, H Yang - Frontiers in Neuroscience, 2022 - frontiersin.org
The human brain has high energetic expenses and consumes over 20% of total oxygen
metabolism. Abnormal brain energy homeostasis leads to various brain diseases. Among …