Obesity and addiction: neurobiological overlaps

ND Volkow, GJ Wang, D Tomasi, RD Baler - Obesity reviews, 2013 - Wiley Online Library
Drug addiction and obesity appear to share several properties. Both can be defined as
disorders in which the saliency of a specific type of reward (food or drug) becomes …

Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity

R Lang, AL Gundlach, FE Holmes, SA Hobson… - Pharmacological …, 2015 - ASPET
Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

The lateral hypothalamus as integrator of metabolic and environmental needs: from electrical self-stimulation to opto-genetics

HR Berthoud, H Münzberg - Physiology & behavior, 2011 - Elsevier
As one of the evolutionary oldest parts of the brain, the diencephalon evolved to harmonize
changing environmental conditions with the internal state for survival of the individual and …

Diet-induced obesity leads to alterations in behavior and gut microbiota composition in mice

REM Júnior, LM de Carvalho, DC Dos Reis… - The Journal of …, 2021 - Elsevier
The high prevalence of obesity and associated metabolic disorders are one of the major
public health problems worldwide. Among the main causal factors of obesity, excessive …

The genetics of familial combined hyperlipidaemia

MCGJ Brouwers, MMJ Van Greevenbroek… - Nature reviews …, 2012 - nature.com
Almost 40 years after the first description of familial combined hyperlipidaemia (FCHL) as a
discrete entity, the genetic and metabolic basis of this prevalent disease has yet to be fully …

Regulation of the mesolimbic dopamine circuit by feeding peptides

S Liu, SL Borgland - Neuroscience, 2015 - Elsevier
Polypeptides produced in the gastrointestinal tract, stomach, adipocytes, pancreas and brain
that influence food intake are referred to as 'feeding-related'peptides. Most peptides that …

Microglia play a role in ethanol‐induced oxidative stress and apoptosis in developing hypothalamic neurons

NI Boyadjieva, DK Sarkar - Alcoholism: Clinical and …, 2013 - Wiley Online Library
Background Animals exposed to alcohol during the developmental period develop many
physiological and behavioral problems because of neuronal loss in various brain areas …

A new gal in town: a systematic review of the role of galanin and its receptors in experimental pain

D Fonseca-Rodrigues, A Almeida, F Pinto-Ribeiro - Cells, 2022 - mdpi.com
Galanin is a neuropeptide expressed in a small percentage of sensory neurons of the dorsal
root ganglia and the superficial lamina of the dorsal horn of the spinal cord. In this work, we …

Cyclic adenosine monophosphate and brain‐derived neurotrophic factor decreased oxidative stress and apoptosis in developing hypothalamic neuronal cells: Role of …

NI Boyadjieva, DK Sarkar - Alcoholism: Clinical and …, 2013 - Wiley Online Library
Background We have previously shown that ethanol (E t OH) increases cellular apoptosis to
developing neurons via the effects on oxidative stress of neurons directly and via increasing …

A history of bingeing on fat enhances cocaine seeking and taking.

MD Puhl, AM Cason, FHE Wojnicki… - Behavioral …, 2011 - psycnet.apa.org
Binge eating and substance dependence are disorders characterized by a loss of control
over consummatory behaviors. Given the common characteristics of these two types of …