Storage of starch and lipids in microalgae: Biosynthesis and manipulation by nutrients

W Ran, H Wang, Y Liu, M Qi, Q Xiang, C Yao… - Bioresource …, 2019 - Elsevier
Microalgae accumulate starch and lipid as storage metabolites under nutrient depletion,
which can be used as sustainable feedstock for biorefinery. Omics analysis coupled with …

Progress of metabolic engineering for the production of eicosapentaenoic acid

YL Jia, SS Geng, F Du, YS Xu, LR Wang… - Critical Reviews in …, 2022 - Taylor & Francis
Eicosapentaenoic Acid (EPA) is an essential ω-3 polyunsaturated fatty acid for human
health. Currently, high-quality EPA production is largely dependent on the extraction of fish …

Function of the Polyketide Synthase Domains of Schizochytrium sp. on Fatty Acid Synthesis in Yarrowia lipolytica

YL Jia, F Du, FT Nong, J Li, PW Huang… - Journal of Agricultural …, 2023 - ACS Publications
It is well known that polyunsaturated fatty acids (PUFAs) in Schizochytrium sp. are mainly
synthesized via the polyketide synthase (PKS) pathway. However, the specific mechanism of …

[HTML][HTML] Time‑resolved transcriptome analysis during transitions of sulfur nutritional status provides insight into triacylglycerol (TAG) and astaxanthin accumulation in …

X Mao, Y Lao, H Sun, X Li, J Yu, F Chen - Biotechnology for biofuels, 2020 - Springer
Background Chromochloris zofingiensis, an oleaginous microalga, is a promising feedstock
for the co-production of triacylglycerol (TAG)-based biodiesel and the high-value product …

Crucial carotenogenic genes elevate hyperaccumulation of both fucoxanthin and β-carotene in Phaeodactylum tricornutum

SY Cen, DW Li, XL Huang, D Huang, S Balamurugan… - Algal Research, 2022 - Elsevier
Burgeoning demand for carotenoids from natural resources has urged to explore the
promising metabolic engineering strategy to improve algal systems. However, existing …

[HTML][HTML] Metabolic Analysis of Schizochytrium Mutants With High DHA Content Achieved With ARTP Mutagenesis Combined With Iodoacetic Acid and …

L Zeng, Y Bi, P Guo, Y Bi, T Wang, L Dong… - … in Bioengineering and …, 2021 - frontiersin.org
High DHA production cost caused by low DHA titer and productivity of the current
Schizochytrium strains is a bottleneck for its application in competition with traditional fish-oil …

[HTML][HTML] Function of ORFC of the polyketide synthase gene cluster on fatty acid accumulation in Schizochytrium limacinum SR21

Y Shi, Z Chen, Y Li, X Cao, L Yang, Y Xu, Z Li… - Biotechnology for …, 2021 - Springer
Background As a potential source of polyunsaturated fatty acids (PUFA), Schizochytrium sp.
has been widely used in industry for PUFA production. Polyketide synthase (PKS) cluster is …

[HTML][HTML] Selecting a preculture strategy for improving biomass and astaxanthin productivity of Chromochloris zofingiensis

Y Wang, J Wang, S Yang, Q Liang, Z Gu… - Applied Microbiology …, 2024 - Springer
Chromochloris zofingiensis is a potential source of natural astaxanthin; however, its rapid
growth and astaxanthin enrichment cannot be achieved simultaneously. This study …

[HTML][HTML] Effects of Coumarin on Rhizosphere Microbiome and Metabolome of Lolium multiflorum

Y Yang, J Xu, Y Li, Y He, Y Yang, D Liu, C Wu - Plants, 2023 - mdpi.com
Rhizosphere microorganisms can help plants absorb nutrients, coordinate their growth, and
improve their environmental adaptability. Coumarin can act as a signaling molecule that …

Regulation of malate-pyruvate pathway unifies the adequate provision of metabolic carbon precursors and NADPH in Tetradesmus obliquus

J Xue, T Li, TT Chen, S Balamurugan, WD Yang, HY Li - Algal Research, 2021 - Elsevier
Metabolic engineering has been hailed as a promising tool to impart oil productivity in fast-
growing microalgae, thereby generating industry-suitable strains. However, complex …