Pseudomonas aeruginosa infection can cause pneumonia and urinary tract infection and
the management of Pseudomonas aeruginosa infection is critical in multidrug resistance …

Natural products are unique sources for drug discovery and exhibit diverse biological
activities. The immunomodulatory properties of natural agents have gained great interest …

Phenylbutyrate (PB), a small aromatic fatty acid, has been known as an interesting
compound with the ability of anti-proliferation and cell growth inhibition in cancer cells. In the …

Abstract Tetraacyldisaccharide 4′-kinase (LpxK) is the prime enzyme responsible for the
biosynthesis of lipid A. LpxK is a key antibacterial drug target, but it is less exploitation in …

Vortioxetine (Vot) is an effective antidepressant with unique mechanisms exerting multi-
target effects. However, severe side-effects such as nausea and vomiting are commonly …

This paper highlights the notable bioactivity and pharmaceutical significance of the natural
furocoumarin viz. Bergapten (BG), extracted from the medicinal plant Melicopedenhamii …

The systematic exploitation of the structural variety of natural products is made possible by
docking studies, which have been shown to be a crucial technique. The objective of the …

The pandemic COVID-19, caused by the organism severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) belongs to the family Coronoviridae has become a serious …

The present study is aimed to analyze lipophilicity and ADMET profiles, and to develop field
based 3D-QSAR and ligand-based pharmacophore hypothesis for a series of 17α-picolyl …

Colon cancer (CC) is one of the most recurrent malignancies. Several decades ago, CC had
a low incidence. Currently, it has become a predominant cancer and contributes in a large …