[HTML][HTML] Hallmarks and biomarkers of skin senescence: An updated review of skin senotherapeutics
D Bulbiankova, R Díaz-Puertas, FJ Álvarez-Martínez… - Antioxidants, 2023 - mdpi.com
Aging is a complex process characterized by an ongoing decline in physiological functions,
leading to degenerative diseases and an increased probability of death. Cellular …
leading to degenerative diseases and an increased probability of death. Cellular …
[HTML][HTML] Senescence: pathogenic driver in chronic obstructive pulmonary disease
M Rivas, G Gupta, L Costanzo, H Ahmed, AE Wyman… - Medicina, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is recognized as a disease of accelerated
lung aging. Over the past two decades, mounting evidence suggests an accumulation of …
lung aging. Over the past two decades, mounting evidence suggests an accumulation of …
Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts
KC Pavani, T Meese, OB Pascottini… - Proceedings of the …, 2022 - National Acad Sciences
Extracellular vesicles (EVs) and their cargo microRNAs (miRNAs) are important regulators of
embryo development to the blastocyst stage and beyond. Before implantation can take …
embryo development to the blastocyst stage and beyond. Before implantation can take …
FBXO43 variants in patients with female infertility characterized by early embryonic arrest
W Wang, W Wang, Y Xu, J Shi, J Fu, B Chen… - Human …, 2021 - academic.oup.com
STUDY QUESTION Can any new genetic factors responsible for early embryonic arrest in
infertile patients be identified, together with the mechanism of pathogenic variants …
infertile patients be identified, together with the mechanism of pathogenic variants …
[HTML][HTML] Endothelial senescence and its impact on angiogenesis in Alzheimer's disease
Endothelial cells are constantly exposed to environmental stress factors that, above a certain
threshold, trigger cellular senescence and apoptosis. The altered vascular function affects …
threshold, trigger cellular senescence and apoptosis. The altered vascular function affects …
[HTML][HTML] Cathepsin-L secreted by high-quality bovine embryos exerts an embryotrophic effect in vitro
While human in vitro embryo production is generally performed individually, animal models
have shown that culturing embryos in groups improves blastocyst yield and quality …
have shown that culturing embryos in groups improves blastocyst yield and quality …
[HTML][HTML] Pre-Implantation Bovine Embryo Evaluation—From Optics to Omics and Beyond
RAC Rabel, PV Marchioretto, EA Bangert, K Wilson… - Animals, 2023 - mdpi.com
Simple Summary With conventional breeding practices, even the best dairy/beef cows will
likely produce no more than half-a-dozen calves in their lifetimes; a crime, would you not …
likely produce no more than half-a-dozen calves in their lifetimes; a crime, would you not …
[HTML][HTML] tRNAGlu-derived fragments from embryonic extracellular vesicles modulate bovine embryo hatching
Y Fan, KC Pavani, K Smits, A Van Soom… - Journal of Animal …, 2024 - Springer
Transfer RNA-derived small RNAs (tsRNAs) have been shown to be involved in early
embryo development and repression of endogenous retroelements in embryos and stem …
embryo development and repression of endogenous retroelements in embryos and stem …
[HTML][HTML] Cumulus cell and oocyte gene expression in prepubertal gilts and sows identifies cumulus cells as a prime informative parameter of oocyte quality
LM Haug, RC Wilson, AH Gaustad, R Jochems… - Biology, 2023 - mdpi.com
Simple Summary Progress has been made in pig in vitro embryo production (IVEP) over the
years, but some of the remaining challenges are low embryo production rates compared to …
years, but some of the remaining challenges are low embryo production rates compared to …
[HTML][HTML] Development of a microfluidic chip powered by EWOD for in vitro manipulation of bovine embryos
A Karcz, A Van Soom, K Smits, S Van Vlierberghe… - Biosensors, 2023 - mdpi.com
Digital microfluidics (DMF) holds great potential for the alleviation of laboratory procedures
in assisted reproductive technologies (ARTs). The electrowetting on dielectric (EWOD) …
in assisted reproductive technologies (ARTs). The electrowetting on dielectric (EWOD) …