[PDF][PDF] The emergence and influence of internal states

SW Flavell, N Gogolla, M Lovett-Barron, M Zelikowsky - Neuron, 2022 - cell.com
Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

[PDF][PDF] Predictive processing: a canonical cortical computation

GB Keller, TD Mrsic-Flogel - Neuron, 2018 - cell.com
This perspective describes predictive processing as a computational framework for
understanding cortical function in the context of emerging evidence, with a focus on sensory …

[HTML][HTML] A transcriptomic axis predicts state modulation of cortical interneurons

S Bugeon, J Duffield, M Dipoppa, A Ritoux, I Prankerd… - Nature, 2022 - nature.com
Transcriptomics has revealed that cortical inhibitory neurons exhibit a great diversity of fine
molecular subtypes,,,,–, but it is not known whether these subtypes have correspondingly …

Spatiotemporally heterogeneous coordination of cholinergic and neocortical activity

S Lohani, AH Moberly, H Benisty, B Landa, M Jing… - Nature …, 2022 - nature.com
Variation in an animal's behavioral state is linked to fluctuations in brain activity and
cognitive ability. In the neocortex, state-dependent circuit dynamics may reflect …

Neuromodulation of brain state and behavior

DA McCormick, DB Nestvogel… - Annual review of …, 2020 - annualreviews.org
Neural activity and behavior are both notoriously variable, with responses differing widely
between repeated presentation of identical stimuli or trials. Recent results in humans and …

Pupil fluctuations track rapid changes in adrenergic and cholinergic activity in cortex

J Reimer, MJ McGinley, Y Liu, C Rodenkirch… - Nature …, 2016 - nature.com
Rapid variations in cortical state during wakefulness have a strong influence on neural and
behavioural responses and are tightly coupled to changes in pupil size across species …

[PDF][PDF] Basal forebrain cholinergic circuits and signaling in cognition and cognitive decline

EC Ballinger, M Ananth, DA Talmage, LW Role - Neuron, 2016 - cell.com
Recent work continues to place cholinergic circuits at center stage for normal executive and
mnemonic functioning and provides compelling evidence that the loss of cholinergic …

The threshold for conscious report: Signal loss and response bias in visual and frontal cortex

B Van Vugt, B Dagnino, D Vartak, H Safaai, S Panzeri… - Science, 2018 - science.org
Why are some visual stimuli consciously detected, whereas others remain subliminal? We
investigated the fate of weak visual stimuli in the visual and frontal cortex of awake monkeys …

[PDF][PDF] Waking state: rapid variations modulate neural and behavioral responses

MJ McGinley, M Vinck, J Reimer, R Batista-Brito… - Neuron, 2015 - cell.com
The state of the brain and body constantly varies on rapid and slow timescales. These
variations contribute to the apparent noisiness of sensory responses at both the neural and …

Mechanisms underlying gain modulation in the cortex

KA Ferguson, JA Cardin - Nature Reviews Neuroscience, 2020 - nature.com
Cortical gain regulation allows neurons to respond adaptively to changing inputs. Neural
gain is modulated by internal and external influences, including attentional and arousal …