Heat stress-induced neuroinflammation and aberration in monoamine levels in hypothalamus are associated with temperature dysregulation

NR Chauhan, M Kapoor, LP Singh, RK Gupta… - Neuroscience, 2017 - Elsevier
Heat Stress (HS) induces diverse pathophysiological changes, which include brain
ischemia, oxidative stress and neuronal damage. The present study was undertaken with …

重症中暑转化医学研究回顾与展望

SU Lei, T Hua-sheng - Jie Fang Jun Yi Xue Za Zhi, 2017 - search.proquest.com
There exist a series of problems in heat stroke treatment, such as, pathogenesis is still
unclear, clinical classification is too simple and has no intrinsic relation with …

Heat stress induced oxidative damage and perturbation in BDNF/ERK1/2/CREB axis in hippocampus impairs spatial memory

NR Chauhan, R Kumar, A Gupta, RC Meena… - Behavioural Brain …, 2021 - Elsevier
Heat exposure is an environmental stress that causes diverse heat related
pathophysiological changes under extreme conditions. The brain including hippocampal …

[HTML][HTML] Aircraft noise, like heat stress, causes cognitive impairments via similar mechanisms in male mice

G Sun, X Lin, X Yi, P Zhang, R Liu, B Fu, Y Sun, J Li… - Chemosphere, 2021 - Elsevier
To our knowledge, little evidence is available about effects of aircraft noise (AN), a non-
chemical stressor, on cognitive function. Again, it is unknown whether or not the heat stress …

Expression profiles of genes associated with inflammatory responses and oxidative stress in lung after heat stroke

Z Liu, J Chen, L Hu, M Li, M Liang, J Chen… - Bioscience …, 2020 - portlandpress.com
Background: Heat stroke (HS) is a physically dysfunctional illness caused by hyperthermia.
Lung, as the important place for gas-exchange and heat-dissipation organ, is often first to be …

Testosterone mediates hyperthermic response of mice to heat exposure

Y Chen, T Yu - Life sciences, 2018 - Elsevier
Aims Testosterone is implicated as a potential contributing factor to heat-induced injury. We
examined effects of testosterone on thermal response of mice to heat exposure. Main …

Dexmedetomidine attenuates acute lung injury induced by heatstroke and improve outcome

Y Geng, R Li, SX He, HH Yang, Q Deng, X Shao, Y Wu… - Shock, 2019 - journals.lww.com
Methods: Male C57BL/6 mice were exposed to ambient temperature of 39.5±0.2 C until core
temperature reach 43 C. DEX or 0.9% saline was injected ip immediately. At the end of the …

Endothelial glycocalyx injury is involved in heatstroke-associated coagulopathy and protected by N-acetylcysteine

N Peng, Y Geng, J Ouyang, S Liu, F Yuan… - Frontiers in …, 2023 - frontiersin.org
Introduction Damage to endothelial glycocalyx (EGCX) can lead to coagulation disorders in
sepsis. Heat stroke (HS) resembles sepsis in many aspects; however, it is unclear whether …

Microcirculatory disorders and protective role of Xuebijing in severe heat stroke

H Jin, Y Chen, C Ding, Y Lin, Y Chen, D Jiang, L Su - Scientific Reports, 2018 - nature.com
This study was conducted to explore underlying mechanism of microcirculation dysfunction
and protectiverole of Xuebijing in heat stroke. Forty rats were divided into: control, vehicle+ …

[HTML][HTML] 经典型及劳力型热射病大鼠心肌损伤对比研究

张伯翼, 罗雪, 罗珍, 王泽泽, 谭雨龙, 何根林, 李萍… - 2023 - aammt.tmmu.edu.cn
目的比较劳力型热射病(exertional heat stroke, EHS) 与经典型热射病(classical heat stroke,
CHS) 大鼠动物模型心肌损伤的差异, 为热射病心肌损伤的临床治疗提供可能的实验室依据 …