Cytokine circuits in cardiovascular disease

JW Williams, L Huang, GJ Randolph - Immunity, 2019 - cell.com
Arterial inflammation is a hallmark of atherosclerosis, and appropriate management of this
inflammation represents a major unmet therapeutic need for cardiovascular disease …

Cell death pathways of particulate matter toxicity

MS Peixoto, MF de Oliveira Galvão, SRB de Medeiros - Chemosphere, 2017 - Elsevier
Humans are exposed to various complex mixtures of particulate matter (PM) from different
sources. Long-term exposure to high levels of these particulates has been linked to a …

[HTML][HTML] Urban particulate matter triggers lung inflammation via the ROS-MAPK-NF-κB signaling pathway

J Wang, J Huang, L Wang, C Chen, D Yang… - Journal of thoracic …, 2017 - ncbi.nlm.nih.gov
Background Particulate matter (PM) is a high risk factor for various respiratory diseases and
triggers an inflammatory response in lung tissues. However, the molecular mechanism of the …

[HTML][HTML] Impact of air pollution on ischemic heart disease: evidence, mechanisms, clinical perspectives

RA Montone, R Rinaldi, A Bonanni, A Severino… - Atherosclerosis, 2023 - Elsevier
Ambient air pollution, and especially particulate matter (PM) air pollution< 2.5 μm in
diameter (PM 2.5), has clearly emerged as an important yet often overlooked risk factor for …

PM2. 5 exposure-induced autophagy is mediated by lncRNA loc146880 which also promotes the migration and invasion of lung cancer cells

X Deng, N Feng, M Zheng, X Ye, H Lin, X Yu… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background Evidence shows that individuals who are under long-term exposure to
environmental PM 2.5 are at increased risk of lung cancer. Various laboratory experiments …

Key characteristics of cardiovascular toxicants

L Lind, JA Araujo, A Barchowsky… - Environmental …, 2021 - ehp.niehs.nih.gov
Background: The concept of chemical agents having properties that confer potential hazard
called key characteristics (KCs) was first developed to identify carcinogenic hazards …

PM2.5 exposure induces systemic inflammation and oxidative stress in an intracranial atherosclerosis rat model

L Guan, X Geng, C Stone, EEP Cosky… - Environmental …, 2019 - Wiley Online Library
Objectives Exposure to airborne particle (PM2. 5) is a risk factor for intracranial
atherosclerosis (ICA). Because of the established role of systemic inflammation and …

Resveratrol alleviates chronic “real-world” ambient particulate matter-induced lung inflammation and fibrosis by inhibiting NLRP3 inflammasome activation in mice

S Ding, H Wang, M Wang, L Bai, P Yu, W Wu - … and environmental safety, 2019 - Elsevier
Resveratrol alleviates chronic “real-world” ambient particulate matter-induced lung
inflammation and fibrosis by inhibiting NLRP3 inflammasome activation in mice …

The association between ambient air pollution and blood lipids: A longitudinal study in Shijiazhuang, China

K Zhang, H Wang, W He, G Chen, P Lu, R Xu… - Science of The Total …, 2021 - Elsevier
Background Few studies have explored the associations between ambient air pollution and
blood lipid levels. This study aimed to fill this knowledge gap based on a routine health …

Effects of ambient particulate matter on vascular tissue: a review

K Shkirkova, K Lamorie-Foote, M Connor… - Journal of Toxicology …, 2020 - Taylor & Francis
Fine and ultra-fine particulate matter (PM) are major constituents of urban air pollution and
recognized risk factors for cardiovascular diseases. This review examined the effects of PM …