5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …

It is now nearly 5 years since the last of the currently recognised 5-HT receptors was
identified in terms of its cDNA sequence. Over this period, much effort has been directed …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

Serotonin (5-hydroxytryptamine, 5-HT) is probably unique among the monoamines in that its
effects are subserved by as many as 13 distinct heptahelical, G-protein-coupled receptors …

Serotonin (5-HT)-receptor-based mechanisms have been postulated to play a critical role in
the action of the new generation of antipsychotic drugs (APDs) that are usually referred to as …

The study of 5-hydroxytryptamine (5-HT) system has benefited from the identification,
classification and cloning of multiple 5-HT receptors (5-HT1 to 5-HT7). Growing evidence …

The 5-hydroxytryptamine6 (5-ht6) was one of the most recent additions to the5-HT receptor
family, selective antagonists have recently been developed and potentialfunctional roles are …

Alzheimer's disease (AD) is a devastating neurological condition characterized by a
progressive decline in cognitive performance accompanied by behavioral and psychological …

Abstract Serotonin (5‐hydroxytryptamine, 5‐HT) mediates a wide variety of physiological
functions by activating multiple receptors, and abnormalities of these receptor systems has …

5-HT6 receptor-like immunoreactivity has been previously found in association with both
neuronal dendrites and cilia in the striatum, nucleus accumbens, olfactory tubercle and …