Ever-present in our environments, light entrains circadian rhythms over long timescales,
influencing daily activity patterns, health and performance. Increasing evidence indicates …

The eight biological hallmarks of health that we initially postulated (Cell. 2021 Jan 7; 184 (1):
33-63) include features of spatial compartmentalization (integrity of barriers, containment of …

Circadian rhythm disruption is closely related to increased incidence of prostate cancer.
Incorporating circadian rhythms into the study of prostate cancer pathogenesis can provide a …

Seasonal rhythms affect the immune system. Evidence supports the involvement of immuno-
inflammatory mechanisms in bipolar disorder (BD), with the neutrophil to lymphocyte ratio …

Circadian rhythms result from cell-intrinsic timing mechanisms that impact health and
disease1, 2. To date, however, neural circadian research has largely focused on the …

This study examined the psychometric properties and longitudinal changes of the self-
reporting Traditional Chinese version of Biological Rhythms Interview for Assessment in …

Circadian system disruption is an essential but poorly understood feature of bipolar disorder
(BD) and associated comorbidities. This forum article summarizes current evidence …

Immune Checkpoint Inhibitors (ICI) have revolutionised cancer care in recent years. Despite
a global improvement in the efficacy and tolerability of systemic anticancer treatments, a …

The circadian clock regulates biological cycles across species and is crucial for
physiological activities and biochemical reactions, including cancer onset and development …

Background: Many patients with bipolar disorder (BD) do not respond to or have difficulties
tolerating lithium and/or other mood stabilizing agents. There is a need for personalized …