[HTML][HTML] An ecotoxicological view on neurotoxicity assessment
The numbers of potential neurotoxicants in the environment are raising and pose a great risk
for humans and the environment. Currently neurotoxicity assessment is mostly performed to …
for humans and the environment. Currently neurotoxicity assessment is mostly performed to …
Approaches to test the neurotoxicity of environmental contaminants in the zebrafish model: From behavior to molecular mechanisms
JA Fitzgerald, S Könemann… - Environmental …, 2021 - Wiley Online Library
The occurrence of neuroactive chemicals in the aquatic environment is on the rise and
poses a potential threat to aquatic biota of currently unpredictable outcome. In particular …
poses a potential threat to aquatic biota of currently unpredictable outcome. In particular …
Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy
High-speed, large-scale three-dimensional (3D) imaging of neuronal activity poses a major
challenge in neuroscience. Here we demonstrate simultaneous functional imaging of …
challenge in neuroscience. Here we demonstrate simultaneous functional imaging of …
[HTML][HTML] Zebrafish behavior: opportunities and challenges
MB Orger, GG de Polavieja - Annual review of neuroscience, 2017 - annualreviews.org
A great challenge in neuroscience is understanding how activity in the brain gives rise to
behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the …
behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the …
Animal models in epilepsy research: legacies and new directions
BP Grone, SC Baraban - Nature neuroscience, 2015 - nature.com
Human epilepsies encompass a wide variety of clinical, behavioral and electrical
manifestations. Correspondingly, studies of this disease in nonhuman animals have brought …
manifestations. Correspondingly, studies of this disease in nonhuman animals have brought …
[HTML][HTML] Whole-brain activity maps reveal stereotyped, distributed networks for visuomotor behavior
Most behaviors, even simple innate reflexes, are mediated by circuits of neurons spanning
areas throughout the brain. However, in most cases, the distribution and dynamics of firing …
areas throughout the brain. However, in most cases, the distribution and dynamics of firing …
[HTML][HTML] Zebrafish models of neurodevelopmental disorders: limitations and benefits of current tools and techniques
R Vaz, W Hofmeister, A Lindstrand - International journal of molecular …, 2019 - mdpi.com
For the past few years there has been an exponential increase in the use of animal models
to confirm the pathogenicity of candidate disease-causing genetic variants found in patients …
to confirm the pathogenicity of candidate disease-causing genetic variants found in patients …
[HTML][HTML] Functional architecture of an optic flow-responsive area that drives horizontal eye movements in zebrafish
Animals respond to whole-field visual motion with compensatory eye and body movements
in order to stabilize both their gaze and position with respect to their surroundings. In …
in order to stabilize both their gaze and position with respect to their surroundings. In …
Integrative whole-brain neuroscience in larval zebrafish
Highlights•Neural activity can now be recorded in all cells of larval zebrafish
brains.•Neurons involved in sensation, motor control, and learning have been …
brains.•Neurons involved in sensation, motor control, and learning have been …
[HTML][HTML] Cerebellar neurodynamics predict decision timing and outcome on the single-trial level
Goal-directed behavior requires the interaction of multiple brain regions. How these regions
and their interactions with brain-wide activity drive action selection is less understood. We …
and their interactions with brain-wide activity drive action selection is less understood. We …