Trial watch: Prognostic and predictive value of the immune infiltrate in cancer

L Senovilla, E Vacchelli, J Galon, S Adjemian… - …, 2012 - Taylor & Francis
Solid tumors are constituted of a variety of cellular components, including bona fide
malignant cells as well as endothelial, structural and immune cells. On one hand, the tumor …

[HTML][HTML] Doubting the TCR coreceptor function of CD8αα

H Cheroutre, F Lambolez - Immunity, 2008 - cell.com
" The beginning of wisdom is found in doubting; by doubting we come to question, and by
seeking we may come upon the truth."–Pierre Abélard CD8 is a glycoprotein expressed on …

An optimized library for reference-based deconvolution of whole-blood biospecimens assayed using the Illumina HumanMethylationEPIC BeadArray

LA Salas, DC Koestler, RA Butler, HM Hansen… - Genome biology, 2018 - Springer
Genome-wide methylation arrays are powerful tools for assessing cell composition of
complex mixtures. We compare three approaches to select reference libraries for …

Multidimensional analyses of donor memory-like NK cells reveal new associations with response after adoptive immunotherapy for leukemia

MM Berrien-Elliott, AF Cashen, CC Cubitt, CC Neal… - Cancer Discovery, 2020 - AACR
Natural killer (NK) cells are an emerging cancer cellular therapy and potent mediators of
antitumor immunity. Cytokine-induced memory-like (ML) NK cellular therapy is safe and …

A novel multiplex bead-based platform highlights the diversity of extracellular vesicles

N Koliha, Y Wiencek, U Heider, C Jüngst… - Journal of …, 2016 - Taylor & Francis
The surface protein composition of extracellular vesicles (EVs) is related to the originating
cell and may play a role in vesicle function. Knowledge of the protein content of individual …

Characterization of circulating T-, NK-, and NKT cell subsets in patients with colorectal cancer: the peripheral blood immune cell profile

D Krijgsman, NL de Vries, A Skovbo… - Cancer Immunology …, 2019 - Springer
Objective As the development and progression of colorectal cancer (CRC) are known to be
affected by the immune system, cell subsets such as T cells, natural killer (NK) cells, and …

γδT cells elicited by CMV reactivation after allo-SCT cross-recognize CMV and leukemia

W Scheper, S van Dorp, S Kersting, F Pietersma… - Leukemia, 2013 - nature.com
Human cytomegalovirus (CMV) infections and relapse of disease remain major problems
after allogeneic stem cell transplantation (allo-SCT), in particular in combination with CMV …

[PDF][PDF] Mass cytometry reveals global immune remodeling with multi-lineage hypersensitivity to type I interferon in Down syndrome

KA Waugh, P Araya, A Pandey, KR Jordan, KP Smith… - Cell reports, 2019 - cell.com
People with Down syndrome (DS; trisomy 21) display a different disease spectrum relative to
the general population, including lower rates of solid malignancies and higher incidence of …

Practical NK cell phenotyping and variability in healthy adults

LS Angelo, PP Banerjee, L Monaco-Shawver… - Immunologic …, 2015 - Springer
Human natural killer (NK) cells display a wide array of surface and intracellular markers that
indicate various states of differentiation and/or levels of effector function. These NK cell …

In vitro immunomodulatory activity of Lactobacillus fermentum CECT5716 and Lactobacillus salivarius CECT5713: two probiotic strains isolated from human breast …

FJ Perez-Cano, H Dong, P Yaqoob - Immunobiology, 2010 - Elsevier
Commensal bacteria, including some species of lactobacilli commonly present in human
breast milk, appear to colonize the neonatal gut and contribute to protection against infant …