[HTML][HTML] Sex differences in methamphetamine use disorder perused from pre-clinical and clinical studies: potential therapeutic impacts

AP Daiwile, S Jayanthi, JL Cadet - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Methamphetamine (METH) use, and misuse are associated with severe socioeconomic
consequences. METH users develop tolerance, lose control over drug taking behaviors, and …

[HTML][HTML] Interaction of gonadal hormones, dopaminergic system, and epigenetic regulation in the generation of sex differences in substance use disorders: A …

R Santos-Toscano, MA Arevalo… - Frontiers in …, 2023 - Elsevier
Substance use disorder (SUD) is a chronic condition characterized by pathological drug-
taking and seeking behaviors. remarkably different between males and females, suggesting …

[HTML][HTML] Sex-dependent effects of chronic intermittent hypoxia: Implication for obstructive sleep apnea

S Mabry, JL Bradshaw, JJ Gardner, EN Wilson… - Biology of sex …, 2024 - Springer
Background Obstructive sleep apnea (OSA) affects 10–26% of adults in the United States
with known sex differences in prevalence and severity. OSA is characterized by elevated …

[HTML][HTML] Intermittent access training produces greater motivation for a non-drug reinforcer than long access training

MM Beasley, T Gunawan, BJ Tunstall, DN Kearns - Learning & behavior, 2022 - Springer
It has recently been proposed that the intermittent access (IntA) drug self-administration
procedure better produces behavioral changes relevant to addiction than the long access …

[HTML][HTML] Therapeutic use and chronic abuse of CNS stimulants and anabolic drugs

D Coliță, CI Coliță, DM Hermann, E Coliță… - Current issues in …, 2022 - mdpi.com
The available evidence suggests that affective disorders, such as depression and anxiety,
increase risk for accelerated cognitive decline and late-life dementia in aging individuals …

Sex-dependent alterations in the mRNA expression of enzymes involved in dopamine synthesis and breakdown after methamphetamine self-administration

AE Miller, AP Daiwile, JL Cadet - Neurotoxicity Research, 2022 - Springer
Sex differences have been reported in methamphetamine (METH) use disorder in humans
and in animal models of METH exposure. Specifically, animals that self-administer METH …

Voluntary oral methamphetamine increases memory deficits and contextual sensitization during abstinence associated with decreased PKMζ and increased κOR in …

JA Avila, N Memos, A Aslan… - Journal of …, 2021 - journals.sagepub.com
Background: Female populations exhibit vulnerabilities to psychostimulant addiction, as well
as cognitive dysfunction following bouts of abuse. Aims: The goal for this study was to …

The effects of alcohol drinking on subsequent methamphetamine self-administration and relapse in adolescent female rats

HL Kline, BK Yamamoto - Behavioural brain research, 2022 - Elsevier
Abstract Alcohol and Methamphetamine (Meth) are widely abused drugs that are frequently
co-abused, though this pattern of polysubstance abuse is rarely studied. Alcohol use during …

Perirhinal to prefrontal circuit in methamphetamine induced recognition memory deficits

JL Hopkins, ST Goldsmith, SK Wood, KH Nelson… - …, 2023 - Elsevier
Return to methamphetamine (meth) use is part of an overarching addictive disorder
hallmarked by cognitive sequela and cortical dysfunction in individuals who use meth …

Age-specific treatment effects of orexin/hypocretin-receptor antagonism on methamphetamine-seeking behavior

NE Zlebnik, NA Holtz, VC Lepak, AT Saykao… - Drug and alcohol …, 2021 - Elsevier
Background Worldwide methamphetamine (METH) use has increased significantly over the
last 10 years, and in the US, METH dependence has sky-rocketed among individuals with …