New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer

ZT Yao, YM Yang, MM Sun, Y He, L Liao… - Cancer …, 2022 - Wiley Online Library
With the development of proteomics and epigenetics, a large number of RNA‐binding
proteins (RBPs) have been discovered in recent years, and the interaction between long …

Regulation of cisplatin resistance in bladder cancer by epigenetic mechanisms

F Li, Z Zheng, W Chen, D Li, H Zhang, Y Zhu… - Drug Resistance …, 2023 - Elsevier
Bladder cancer is one of the most common malignancies in the world. Cisplatin is one of the
most potent and widely used anticancer drugs and has been employed in several …

Non-coding RNAs and potential therapeutic targeting in cancer

S Toden, TJ Zumwalt, A Goel - … et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
Recent advances have begun to clarify the physiological and pathological roles of non-
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …

Non-coding RNAs as drug targets

M Matsui, DR Corey - Nature reviews Drug discovery, 2017 - nature.com
Most of the human genome encodes RNAs that do not code for proteins. These non-coding
RNAs (ncRNAs) may affect normal gene expression and disease progression, making them …

The long noncoding RNA Malat1: Its physiological and pathophysiological functions

X Zhang, MH Hamblin, KJ Yin - RNA biology, 2017 - Taylor & Francis
Recent studies suggest that in humans, DNA sequences responsible for protein coding
regions comprise only 2% of the total genome. The rest of the transcripts result in RNA …

New Insights into Long Non-Coding RNA MALAT1 in Cancer and Metastasis

Y Sun, L Ma - Cancers, 2019 - mdpi.com
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is one of the most
abundant, long non-coding RNAs (lncRNAs) in normal tissues. This lncRNA is highly …

MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches

N Amodio, L Raimondi, G Juli, MA Stamato… - Journal of hematology & …, 2018 - Springer
The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …

MALAT1 Long Non-Coding RNA: Functional Implications

G Arun, D Aggarwal, DL Spector - Non-coding RNA, 2020 - mdpi.com
The mammalian genome is pervasively transcribed and the functional significance of many
long non-coding RNA (lncRNA) transcripts are gradually being elucidated. Metastasis …

Exosome–transmitted long non-coding RNA PTENP1 suppresses bladder cancer progression

R Zheng, M Du, X Wang, W Xu, J Liang, W Wang, Q Lv… - Molecular cancer, 2018 - Springer
Background Extracellular communication within the tumor microenvironment plays a critical
role in tumor progression. Although exosomes can package into long non-coding RNAs …

MALAT1: a potential biomarker in cancer

ZX Li, QN Zhu, HB Zhang, Y Hu, G Wang… - Cancer management …, 2018 - Taylor & Francis
Purpose The research of long non-coding RNAs (lncRNAs) has become a new passion with
the discovery of abundant new lncRNAs and extensive investigation of their roles in various …