Microenvironment‐based diabetic foot ulcer nanomedicine

F Huang, X Lu, Y Yang, Y Yang, Y Li, L Kuai… - Advanced …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFU), one of the most serious complications of diabetes, are essentially
chronic, nonhealing wounds caused by diabetic neuropathy, vascular disease, and bacterial …

Advances of hydrogel dressings in diabetic wounds

H Wang, Z Xu, M Zhao, G Liu, J Wu - Biomaterials science, 2021 - pubs.rsc.org
Currently, the treatment and care of diabetic wounds, which generally possess the
characteristics of a high amputation rate, high recurrence rate and high mortality, has …

Advanced drug delivery systems and artificial skin grafts for skin wound healing

HS Kim, X Sun, JH Lee, HW Kim, X Fu… - Advanced drug delivery …, 2019 - Elsevier
Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …

Emerging treatment strategies in wound care

M Mirhaj, S Labbaf, M Tavakoli… - International Wound …, 2022 - Wiley Online Library
Wound healing is a complex process in tissue regeneration through which the body
responds to the dissipated cells as a result of any kind of severe injury. Diabetic and non …

Biofilms: formation, research models, potential targets, and methods for prevention and treatment

Y Su, JT Yrastorza, M Matis, J Cusick, S Zhao… - Advanced …, 2022 - Wiley Online Library
Due to the continuous rise in biofilm‐related infections, biofilms seriously threaten human
health. The formation of biofilms makes conventional antibiotics ineffective and dampens …

A 0D-2D heterojunction bismuth molybdate-anchored multifunctional hydrogel for highly efficient eradication of drug-resistant bacteria

X Wang, Q Li, Y Miao, X Chen, X Zhang, J Shi, F Liu… - ACS …, 2023 - ACS Publications
Due to the increasing antibiotic resistance and the lack of broad-spectrum antibiotics, there
is an urgent requirement to develop fresh strategies to combat multidrug-resistant …

Construction of multifunctional wound dressings with their application in chronic wound treatment

L Long, W Liu, C Hu, L Yang, Y Wang - Biomaterials science, 2022 - pubs.rsc.org
As the prevalence of diabetes increases year by year and the aging population continues to
intensify in the world, chronic wounds such as diabetic foot ulcers and pressure ulcers have …

Biofilms in chronic wounds: pathogenesis and diagnosis

YK Wu, NC Cheng, CM Cheng - Trends in biotechnology, 2019 - cell.com
Chronic non-healing wounds have become a major worldwide healthcare burden. The
impact of biofilms on chronic wound infection is well established. Despite increasing …

The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms

A de Breij, M Riool, RA Cordfunke… - Science translational …, 2018 - science.org
Development of novel antimicrobial agents is a top priority in the fight against multidrug-
resistant (MDR) and persistent bacteria. We developed a panel of synthetic antimicrobial …

From antibacterial to antibiofilm targeting: an emerging paradigm shift in the development of quaternary ammonium compounds (QACs)

EA Saverina, NA Frolov, OA Kamanina… - ACS Infectious …, 2023 - ACS Publications
In a previous development stage, mostly individual antibacterial activity was a target in the
optimization of biologically active compounds and antiseptic agents. Although this targeting …