Cardiovascular disease, with atherosclerosis as the major underlying factor, remains the
leading cause of death worldwide. It is well established that cholesterol ester-enriched foam …

Hyperlipidemia, defined as the presence of excess fat or lipids in the blood, has been
considered as a high-risk factor and key indicator of many metabolic diseases. The gut …

The E4 allele of the apolipoprotein E gene (APOE) has been established as a genetic risk
factor for many diseases including cardiovascular diseases and Alzheimer's disease (AD) …

We consider our current understanding and therapy of cardiovascular diseases (CVD) state-
of-the-art, but heart disease is still a problem because there is still a lot that we do not know …

Moreover, over the last few years the approach to treatment of patients with a high
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …

Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

Background Diabetes and cardiovascular disease are two of the main causes of death in the
United States. Identifying and predicting these diseases in patients is the first step towards …

High-throughput targeted lipid profiling with liquid chromatography-mass spectrometry (LC-
MS) has been used extensively to identify associations between plasma lipid species and …

Background: Emerging evidence suggests that elevated circulating levels of HDL-C (high-
density lipoprotein cholesterol) could be linked to an increased mortality risk. However, to …

The bioactive ingredients in commonly consumed foods include, but are not limited to,
prebiotics, prebiotic‐like components, probiotics, and postbiotics. The bioactive ingredients …