Genetic factors as potential molecular markers of human oocyte and embryo quality
Q Sang, Z Zhou, J Mu, L Wang - Journal of Assisted Reproduction and …, 2021 - Springer
Successful human reproduction requires gamete maturation, fertilization, and early
embryonic development. Human oocyte maturation includes nuclear and cytoplasmic …
embryonic development. Human oocyte maturation includes nuclear and cytoplasmic …
Meiosis interrupted: the genetics of female infertility via meiotic failure
Idiopathic or “unexplained” infertility represents as many as 30% of infertility cases
worldwide. Conception, implantation, and term delivery of developmentally healthy infants …
worldwide. Conception, implantation, and term delivery of developmentally healthy infants …
Homozygous mutations in BTG4 cause zygotic cleavage failure and female infertility
W Zheng, Z Zhou, Q Sha, X Niu, X Sun, J Shi… - The American Journal of …, 2020 - cell.com
Zygotic cleavage failure (ZCF) is a unique early embryonic phenotype resulting in female
infertility and recurrent failure of in vitro fertilization (IVF) and/or intracytoplasmic sperm …
infertility and recurrent failure of in vitro fertilization (IVF) and/or intracytoplasmic sperm …
Preconception genome medicine: current state and future perspectives to improve infertility diagnosis and reproductive and health outcomes based on individual …
A Capalbo, M Poli, A Riera-Escamilla… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Our genetic code is now readable, writable and hackable. The recent
escalation of genome-wide sequencing (GS) applications in population diagnostics will not …
escalation of genome-wide sequencing (GS) applications in population diagnostics will not …
Implications of environmental toxicants on ovarian follicles: how it can adversely affect the female fertility?
The pool of primordial follicles formed in the ovaries during early development determines
the span and quality of fertility in the reproductive life of a woman. As exposure to …
the span and quality of fertility in the reproductive life of a woman. As exposure to …
A multi-omics analysis identifies molecular features associated with fertility in heifers (Bos taurus)
MA Marrella, FH Biase - Scientific Reports, 2023 - nature.com
Infertility or subfertility is a critical barrier to sustainable cattle production, including in heifers.
The development of heifers that do not produce a calf within an optimum window of time is a …
The development of heifers that do not produce a calf within an optimum window of time is a …
Genetics of oocyte maturation defects and early embryo development arrest
OA Solovova, VB Chernykh - Genes, 2022 - mdpi.com
Various pathogenic factors can lead to oogenesis failure and seriously affect both female
reproductive health and fertility. Genetic factors play an important role in folliculogenesis and …
reproductive health and fertility. Genetic factors play an important role in folliculogenesis and …
Meiotic chromosome structure, the synaptonemal complex, and infertility
In meiosis, homologous chromosome synapsis is mediated by a supramolecular protein
structure, the synaptonemal complex (SC), that assembles between homologous …
structure, the synaptonemal complex (SC), that assembles between homologous …
Maternal effect genes: Update and review of evidence for a link with birth defects
LE Mitchell - Human Genetics and Genomics Advances, 2022 - cell.com
Maternal effect genes (MEGs) encode factors (eg, RNA) that are present in the oocyte and
required for early embryonic development. Hence, while these genes and gene products are …
required for early embryonic development. Hence, while these genes and gene products are …
Microarray and in silico analysis of DNA repair genes between human testis of patients with nonobstructive azoospermia and normal cells
D Hashemi Karoii, H Azizi… - Cell Biochemistry and …, 2022 - Wiley Online Library
DNA repair processes are critical to maintaining genomic integrity. As a result, dysregulation
of repair genes is likely to be linked with health implications, such as an increased …
of repair genes is likely to be linked with health implications, such as an increased …