[HTML][HTML] Sympathetic nervous system activation and heart failure: Current state of evidence and the pathophysiology in the light of novel biomarkers

JA Borovac, D D'Amario, J Bozic… - World journal of …, 2020 - ncbi.nlm.nih.gov
Heart failure (HF) is a complex clinical syndrome characterized by the activation of at least
several neurohumoral pathways that have a common role in maintaining cardiac output and …

[HTML][HTML] The role of neuropeptide Y in cardiovascular health and disease

CMJ Tan, P Green, N Tapoulal… - Frontiers in …, 2018 - frontiersin.org
Neuropeptide Y (NPY) is an abundant sympathetic co-transmitter, widely found in the central
and peripheral nervous systems and with diverse roles in multiple physiological processes …

[HTML][HTML] Neurochemical evidence of cardiac sympathetic activation and increased central nervous system norepinephrine turnover in severe congestive heart failure

DM Kaye, GW Lambert, J Lefkovits, M Morris… - Journal of the American …, 1994 - Elsevier
Objectives. The aim of this study was to characterize cardiac sympathetic nervous function in
patients with severe heart failure and to investigate the influence of the cause of heart …

[HTML][HTML] Neuropeptide Y and metabolism syndrome: an update on perspectives of clinical therapeutic intervention strategies

Y Huang, X Lin, S Lin - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Through the past decade of research, the pathogenic mechanisms underlying metabolic
syndrome have been suggested to involve not only the peripheral tissues, but also central …

Signaling and function of cardiac autonomic nervous system receptors: Insights from the GPCR signalling universe

A Lymperopoulos, N Cora, J Maning, AR Brill… - The FEBS …, 2021 - Wiley Online Library
The two branches of the autonomic nervous system (ANS), adrenergic and cholinergic, exert
a multitude of effects on the human myocardium thanks to the activation of distinct G protein …

Autonomic pathophysiology in heart failure patients. Sympathetic-cholinergic interrelations.

TR Porter, DL Eckberg, JM Fritsch… - The Journal of …, 1990 - Am Soc Clin Investig
We conducted this study in an effort to characterize and understand vagal abnormalities in
heart failure patients whose sympathetic activity is known. We measured sympathetic …

Neuroimmune crosstalk in the pathophysiology of hypertension

L Calvillo, MM Gironacci, L Crotti, PL Meroni… - Nature reviews …, 2019 - nature.com
Hypertension is an important risk factor for cardiovascular morbidity and mortality and for
events such as myocardial infarction, stroke, heart failure and chronic kidney disease and is …

[HTML][HTML] Autonomic control of ventricular function in health and disease: current state of the art

VYH van Weperen, CM Ripplinger… - Clinical Autonomic …, 2023 - Springer
Purpose Cardiac autonomic dysfunction is one of the main pillars of cardiovascular
pathophysiology. The purpose of this review is to provide an overview of the current state of …

Region-specific neuropeptide Y overflows at rest and during sympathetic activation in humans

MJ Morris, HS Cox, GW Lambert, DM Kaye… - …, 1997 - Am Heart Assoc
Neuropeptide Y coexists with norepinephrine in sympathetic nerves and is coreleased into
the circulation on sympathetic activation. Little is known about the regional release of …

The role of neuropeptide Y in cardiovascular regulation

P Walker, E Grouzmann, M Burnier… - Trends in pharmacological …, 1991 - cell.com
Neumpeptidc Y (NPYJ is a 36 amino acid prptide present in the brain, the adrenal medulla
and peripheral sympathetic nerves. The localization and mode of release of NPY led to the …