[HTML][HTML] The cardiac sympathetic co-transmitter galanin reduces acetylcholine release and vagal bradycardia: implications for neural control of cardiac excitability
The autonomic phenotype of congestive cardiac failure is characterised by high sympathetic
drive and impaired vagal tone, which are independent predictors of mortality. We …
drive and impaired vagal tone, which are independent predictors of mortality. We …
The role of neuropeptide Y in cardiovascular regulation
P Walker, E Grouzmann, M Burnier… - Trends in pharmacological …, 1991 - cell.com
Neumpeptidc Y (NPYJ is a 36 amino acid prptide present in the brain, the adrenal medulla
and peripheral sympathetic nerves. The localization and mode of release of NPY led to the …
and peripheral sympathetic nerves. The localization and mode of release of NPY led to the …
Regional sympathetic effects of low-dose clonidine in heart failure
This study examined the effects of low doses of intravenous clonidine on regional and global
sympathetic nervous system activity in heart failure. In heart failure, adrenoceptor-blocking …
sympathetic nervous system activity in heart failure. In heart failure, adrenoceptor-blocking …
[HTML][HTML] Cardiac sympathetic activation circumvents high-dose beta blocker therapy in part through release of neuropeptide Y
JD Hoang, S Salavatian, N Yamaguchi, MA Swid… - JCI insight, 2020 - ncbi.nlm.nih.gov
The sympathetic nervous system plays an important role in the occurrence of ventricular
tachycardia (VT). Many patients, however, experience VT despite maximal doses of beta …
tachycardia (VT). Many patients, however, experience VT despite maximal doses of beta …
Neuropeptide Y reduces acetylcholine release and vagal bradycardia via a Y2 receptor-mediated, protein kinase C-dependent pathway
N Herring, MN Lokale, EJ Danson, DA Heaton… - Journal of molecular and …, 2008 - Elsevier
The co-transmitter neuropeptide Y (NPY), released during prolonged cardiac sympathetic
nerve stimulation, can attenuate vagal-induced bradycardia. We tested the hypothesis that …
nerve stimulation, can attenuate vagal-induced bradycardia. We tested the hypothesis that …
Agonist‐induced desensitisation of β3‐adrenoceptors: Where, when, and how?
β3‐Adrenoceptor agonists have proven useful in the treatment of overactive bladder
syndrome, but it is not known whether their efficacy during chronic administration may be …
syndrome, but it is not known whether their efficacy during chronic administration may be …
Low urinary 6-sulfatoxymelatonin levels in patients with severe congestive heart failure
L Girotti, M Lago, O Ianovsky, MV Elizari, A Dini… - Endocrine, 2003 - Springer
Objective: To assess urinary 6-sulfatoxymelatonin excretion in patients admitted to the
hospital because of congestive heart failure (CHF). Methods: Urinary 6-sulfatoxymelatonin …
hospital because of congestive heart failure (CHF). Methods: Urinary 6-sulfatoxymelatonin …
Adrenomedullin, endothelin, neuropeptide Y, atrial, brain, and C-natriuretic prohormone peptides compared as early heart failure indicators
S Daggubati, JR Parks, RM Overton… - Cardiovascular …, 1997 - academic.oup.com
Objectives: The present investigation was designed to determine the best endogenous
plasma marker of early congestive heart failure (CHF). Methods: Forty volunteers with mild …
plasma marker of early congestive heart failure (CHF). Methods: Forty volunteers with mild …
Evidence for functional presynaptic alpha-2 adrenoceptors and their down-regulation in human heart failure
A Aggarwal, MD Esler, F Socratous, DM Kaye - Journal of the American …, 2001 - jacc.org
OBJECTIVES The aim of this study was to investigate the role of peripheral presynaptic
alpha-2 adrenergic receptors in modulating norepinephrine (NE) release in congestive heart …
alpha-2 adrenergic receptors in modulating norepinephrine (NE) release in congestive heart …
Renal effects of neuropeptide Y
A Bischoff, MC Michel - Pflügers Archiv, 1998 - Springer
Neuropeptide Y (NPY) is a co-transmitter of the sympathetic nervous system including the
renal nerves. The kidney expresses NPY receptors, which can also be activated by peptide …
renal nerves. The kidney expresses NPY receptors, which can also be activated by peptide …