[HTML][HTML] Animal models of acute exacerbation of pulmonary fibrosis

X Ye, M Zhang, H Gu, M Liu, Y Zhao, Y Shi, S Wu… - Respiratory …, 2023 - Springer
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive scarring interstitial lung disease
with an unknown cause. Some patients may experience acute exacerbations (AE), which …

Molecular and immune signatures, and pathological trajectories of fatal COVID‐19 lungs defined by in situ spatial single‐cell transcriptome analysis

A Das, W Meng, Z Liu, MM Hasib… - Journal of Medical …, 2023 - Wiley Online Library
Despite intensive studies during the last 3 years, the pathology and underlying molecular
mechanism of coronavirus disease 2019 (COVID‐19) remain poorly defined. In this study …

Variations in S100A8/A12 Gene Expression Are Associated with the Efficacy of Nintedanib and Acute Exacerbation Development in Idiopathic Pulmonary Fibrosis …

N Arai, M Nakajima, M Matsuyama… - American Journal of …, 2023 - atsjournals.org
Nintedanib is now used worldwide as an antifibrotic drug to treat patients with idiopathic
pulmonary fibrosis (IPF). In INPULSIS-2 (Safety and Efficacy of BIBF 1120 at High Dose in …

[HTML][HTML] RAGE Against the Glycation Machine in Synucleinopathies: Time to Explore New Questions

DP Gelain, RR Bittencourt… - Journal of …, 2023 - content.iospress.com
Oligomerization and aggregation of misfolded forms of α-synuclein are believed to be key
molecular mechanisms in Parkinson's disease (PD) and other synucleinopathies, so …

Cellular and molecular heterogeneities and signatures, and pathological trajectories of fatal COVID-19 lungs defined by spatial single-cell transcriptome analysis

A Das, W Meng, Z Liu, MM Hasib, H Galloway… - medRxiv, 2023 - medrxiv.org
Despite intensive studies during the last 3 years, the pathology and underlying molecular
mechanism of coronavirus disease 2019 (COVID-19) remain poorly defined. Here, we …

[HTML][HTML] Analysis of the Potential Relationship between Aging and Pulmonary Fibrosis Based on Transcriptome

S Fu, X Tang, Y Xu, X Song, X Qian, Y Hu, M Zhang - Life, 2022 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is an age-related interstitial lung disease with a high
incidence in the elderly. Although many reports have shown that senescence can initiate …

[引用][C] Breath of fresh air: Investigating the link between AGEs, sRAGE, and lung diseases

C Delrue, R Speeckaert, JR Delanghe, MM Speeckaert - 2024 - Elsevier