Iron overload induces colitis by modulating ferroptosis and interfering gut microbiota in mice

K Gu, A Wu, B Yu, T Zhang, X Lai, J Chen, H Yan… - Science of The Total …, 2023 - Elsevier
Background Iron plays a pivotal role in various physiological processes, including intestinal
inflammation, ferroptosis, and the modulation of the gut microbiome. However, the way these …

Mechanistic perspective on the actions of vitamin a in autism spectrum disorder etiology

R Carrazana, F Espinoza, A Ávila - Neuroscience, 2024 - Elsevier
Vitamin A (VA) has many functions in the body, some of which are key for the development
and functioning of the nervous system, while some others might indirectly influence neural …

The effect and mechanism of combined exposure of MC-LR and NaNO2 on liver lipid metabolism

J Yang, Z Zhang, X Du, Y Wang, R Meng, K Ge… - Environmental …, 2024 - Elsevier
Abstract Microcystin-LR (MC-LR) and sodium nitrite (NaNO 2) co-exist in the environment
and are hepatotoxic. The liver has the function of lipid metabolism, but the impacts and …

[HTML][HTML] Human umbilical cord mesenchymal stem cells protect against ferroptosis in acute liver failure through the IGF1-hepcidin-FPN1 axis and inhibiting iron …

H Cheng, Y Shi, X Li, N Jin, M Zhang, Z Liu… - Acta Biochimica et …, 2024 - ncbi.nlm.nih.gov
Acute liver failure (ALF) is a significant global issue with elevated morbidity and mortality
rates. There is an urgent and pressing need for secure and effective treatments. Ferroptosis …

TaoHe ChengQi decoction ameliorates sepsis-induced cardiac dysfunction through anti-ferroptosis via the Nrf2 pathway

S Lu, B Yang, Z Tan, H Wang, M Xie, W Jiang, J Huang… - Phytomedicine, 2024 - Elsevier
Background Sepsis-induced cardiac dysfunction (SICD) is a serious complication of sepsis
that is associated with increased mortality. Ferroptosis has been reported in the SICD …

Cryptotanshinone Inhibits Bladder Cancer Cell Malignant Progression in a Lipopolysaccharide‐Induced Inflammatory Microenvironment through NLRP3 Inhibition

C Tang, X Guo, Y Li, Y Yi, Z Tang… - Mediators of …, 2024 - Wiley Online Library
Background. Bladder cancer (BC) is one of the most common malignancies of the urogenital
system. This study assessed the nucleotide‐binding oligomerization domain and leucine …

[HTML][HTML] Retinoic acid alleviates rotavirus-induced intestinal damage by regulating redox homeostasis and autophagic flux in piglets

X Lai, A Wu, B Yu, H Yan, J Luo, P Zheng, J Yu… - Animal Nutrition, 2024 - Elsevier
Rotaviruses (RV) are a major cause of severe gastroenteritis, particularly in neonatal piglets.
Despite the availability of effective vaccines, the development of antiviral therapies for RV …

Ecdysteroids-Enriched Fraction of Cyathula Officinalis KC Kuan Suppresses Synovial Proliferation and Inflammation to Ameliorate Ra by Inhibiting the Akt/Pi3k/Mtor …

Y Huang, L Qiu, Y Peng, Q Xiao, M Li, L Xu - papers.ssrn.com
Rheumatoid arthritis (RA), a chronic and complex joint disease, is characterized by tumor-
like expansion of the synovial tissue as well as persistent and destructive inflammation of the …