[HTML][HTML] The role of oxidative stress in atherosclerosis

M Batty, MR Bennett, E Yu - Cells, 2022 - mdpi.com
Atherosclerosis is a chronic inflammatory disease of the vascular system and is the leading
cause of cardiovascular diseases worldwide. Excessive generation of reactive oxygen …

[HTML][HTML] The multifunctional role of herbal products in the management of diabetes and obesity: a comprehensive review

MM Rahman, MR Islam, S Shohag, ME Hossain… - Molecules, 2022 - mdpi.com
Obesity and diabetes are the most demanding health problems today, and their prevalence,
as well as comorbidities, is on the rise all over the world. As time goes on, both are …

[HTML][HTML] Is Alzheimer's disease a type 3 diabetes? A critical appraisal

R Kandimalla, V Thirumala, PH Reddy - Biochimica et Biophysica Acta …, 2017 - Elsevier
Recently researchers proposed the term 'Type-3-Diabetes' for Alzheimer's disease (ad)
because of the shared molecular and cellular features among Type-1-Diabetes, Type-2 …

[HTML][HTML] Molecular regulation of adipogenesis and potential anti-adipogenic bioactive molecules

D Moseti, A Regassa, WK Kim - International journal of molecular …, 2016 - mdpi.com
Adipogenesis is the process by which precursor stem cells differentiate into lipid laden
adipocytes. Adipogenesis is regulated by a complex and highly orchestrated gene …

Short-chain fatty acids protect against high-fat diet–induced obesity via a PPARγ-dependent switch from lipogenesis to fat oxidation

G Den Besten, A Bleeker, A Gerding, K van Eunen… - Diabetes, 2015 - Am Diabetes Assoc
Short-chain fatty acids (SCFAs) are the main products of dietary fiber fermentation and are
believed to drive the fiber-related prevention of the metabolic syndrome. Here we show that …

Oxidative stress and the pathogenesis of Alzheimer′ s disease

Y Zhao, B Zhao - Oxidative medicine and cellular longevity, 2013 - Wiley Online Library
Alzheimer′ s disease (AD) is the most common neurodegenerative disease that causes
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …

The oxidative stress and mitochondrial dysfunction during the pathogenesis of diabetic retinopathy

MY Wu, GT Yiang, TT Lai, CJ Li - Oxidative medicine and …, 2018 - Wiley Online Library
Diabetic retinopathy is one of the most serious microvascular complications induced by
hyperglycemia via five major pathways, including polyol, hexosamine, protein kinase C, and …

Targeting hepatic glucose metabolism in the treatment of type 2 diabetes

AK Rines, K Sharabi, CDJ Tavares… - Nature reviews Drug …, 2016 - nature.com
Type 2 diabetes mellitus is characterized by the dysregulation of glucose homeostasis,
resulting in hyperglycaemia. Although current diabetes treatments have exhibited some …

Oxidative stress, insulin signaling, and diabetes

JL Rains, SK Jain - Free radical biology and medicine, 2011 - Elsevier
Oxidative stress has been implicated as a contributor to both the onset and the progression
of diabetes and its associated complications. Some of the consequences of an oxidative …

Myocardial fatty acid metabolism in health and disease

GD Lopaschuk, JR Ussher, CDL Folmes… - Physiological …, 2010 - journals.physiology.org
There is a constant high demand for energy to sustain the continuous contractile activity of
the heart, which is met primarily by the β-oxidation of long-chain fatty acids. The control of …