In work spanning more than a century, mitochondria have been recognized for their
multifunctional roles in metabolism, energy transduction, ion transport, inheritance …

Cancer cells have an abnormally high mitochondrial membrane potential (ΔΨm), which is
associated with enhanced invasive properties in vitro and increased metastases in vivo. The …

Brown adipose tissue (BAT) is an energy-expending organ that produces heat. Expansion or
activation of BAT prevents obesity and diabetes. Chronic cold exposure enhances …

ABSTRACT GORE, CJ, SA CLARK, and PU SAUNDERS. Nonhematological Mechanisms of
Improved Sea-Level Performance after Hypoxic Exposure. Med. Sci. Sports Exerc., Vol. 39 …

C57BL/6 (B6) mice subjected to a high-fat diet develop metabolic syndrome with obesity,
hyperglycemia, and insulin resistance, whereas 129S6/SvEvTac (129) mice are relatively …

Apelin, the endogenous ligand of the APJ receptor, has been identified in a variety of
tissues, including stomach, heart, skeletal muscle, and white adipose tissue. We sought to …

Exposure to ambient fine particulate matter (PM2. 5) increases the risk of respiratory
disease. Although previous mitochondrial research has provided new information about PM …

BACKGROUND & AIMS: Fatty acid ethyl esters are ethanol metabolites inducing sustained,
toxic elevations of the acinar cytosolic free calcium ion concentration ([Ca2+] C) implicated …

Emergence of thermogenic adipocytes such as brown and beige adipocytes is critical for
whole body energy metabolism. Promoting the emergence of these adipocytes, which …

Oleanolic (OA), ursolic (UA), and betulinic (BA) acids are three triterpenic acids (TAs) with
potential effects for treatment of type 2 diabetes (T2DM). Mechanistic studies showed that …