Brown and beige adipose tissues are the primary sites for adaptive non-shivering
thermogenesis. Although they have been known principally for their thermogenic effects, in …

The accumulation of oxidative damage to DNA and other biomolecules plays an important
role in the etiology of aging and age-related diseases such as type 2 diabetes mellitus …

Cold constricts cutaneous blood vessels by selectively increasing the activity of smooth
muscle α2-adrenoceptors (α2-ARs). In mouse tail arteries, α2-AR constriction is mediated by …

Obesity is an excess accumulation of adipose tissue mass, and, together with its sequelae,
in particular type II diabetes and metabolic syndrome, obesity presents a major health crisis …

Breast cancer is the most common malignancy in women worldwide, with a developmental
process spanning decades. The malignant cells recruit a variety of cells including …

Wooden breast is one of several myopathies of fast-growing commercial broilers that has
emerged as a consequence of intensive selection practices in the poultry breeding industry …

Thyroid hormones (TH) are of central importance for thermogenesis, energy homeostasis
and metabolism. Here, we will discuss these aspects by focussing on the physiological …

Pyroptosis is a novel pro-inflammatory cell programmed death dependent on Gasdermin
(GSMD) family-mediated membrane pore formation and subsequent cell lysis, accompanied …

Stearoyl-CoA desaturase-1 (SCD1) catalyzes the synthesis of monounsaturated fatty acids
and is an important regulator of whole body energy homeostasis. Severe cutaneous …

The three βAR (β-adrenergic receptor) subtypes (β1AR, β2AR, and β3AR) are members of
the large family of G protein-coupled receptors, each of which is coupled to Gαs and …